Bilateral basal ganglia calcification was noted in 2 patients with primary nonfamilial hyperparathyroidism and very similar neurological syndromes. Neurologic abnormalities consisted primarily of parkinsonian features, gait apraxia and frontal lobe dysfunction. In 1 patient, parathyroidectomy was followed by distinct neurological improvement and the virtual disappearance of intracranial calcification. Parathyroid hormone has effects on neurological function and brain calcium content, and may result in clinically significant but reversible basal ganglia calcification.
|Original language||English (US)|
|Number of pages||7|
|Journal||Mineral and Electrolyte Metabolism|
|State||Published - Jan 1 1981|
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism