Abstract
11 patients with kidney stone disease and idiopathic hypercalciuria (urinary calcium above 4 mg/kg/j), without phosphorus renal leak and 6 control subjects were put for 3 days on a diet containing 1 g calcium and 1 phosphorus daily (period A), and then for 4 days on a diet containing 1 g calcium, 450 mg phosphorus and 3 g aluminium hydroxide daily (period B). During period A, no significant difference in blood calcium, phosphorus and magnesium, phosphaturia, rate of phosphorus reabsorption (RPR) and ratio maximum RPR/creatinine clearance was found between the two groups. After 2 days on a low phosphate diet (period B) the blood phosphorus decreased significantly in the hypercalciuric patients thus revealing a latent abnormality in the retention of phosphates in them. This abnormality could play an important role in the pathogenesis of hypercalciuria.
| Translated title of the contribution | Idiopathic hypercalciuria: Effects of acute phosphorus deficiency |
|---|---|
| Original language | French |
| Pages (from-to) | 3619-3622 |
| Number of pages | 4 |
| Journal | Nouvelle Presse Medicale |
| Volume | 8 |
| Issue number | 44 |
| State | Published - 1979 |
| Externally published | Yes |
ASJC Scopus subject areas
- General Medicine