Huntington's disease: A decade beyond gene discovery

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Huntington's disease is a dominantly inherited neurodegenerative disease that causes a progressive movement disorder, cognitive decline, and varying degrees of psychiatric dysfunction. The identification of the mutant gene in 1993 paved the way for a decade of basic research. The resultant advances in our understanding of the pathogenesis of the disorder are moving us toward rational therapies to slow the progression and delay the onset of the illness.

Original languageEnglish (US)
Pages (from-to)279-284
Number of pages6
JournalCurrent Neurology and Neuroscience Reports
Volume3
Issue number4
StatePublished - Jul 2003

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Huntington Disease
Movement Disorders
Genetic Association Studies
Neurodegenerative Diseases
Psychiatry
Research
Genes
Therapeutics
Cognitive Dysfunction

ASJC Scopus subject areas

  • Medicine(all)
  • Neuroscience(all)

Cite this

Huntington's disease : A decade beyond gene discovery. / Hogarth, Penelope (Penny).

In: Current Neurology and Neuroscience Reports, Vol. 3, No. 4, 07.2003, p. 279-284.

Research output: Contribution to journalArticle

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