@article{79aae65b1f51433db40c318fefbd08fe,
title = "Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets",
abstract = "Cassetta et al. identify a breast cancer tumor-associated macrophage (TAM) transcriptome that is different from those of monocytes and tissue-resident macrophages, and which is associated with shorter disease-specific survival, and they demonstrate crosstalk between tumor cells and TAMs via SIGLEC1, CCL8, and CSF1.",
keywords = "CCL8, SIGLEC1, breast cancer, endometrial cancer, human circulating monocytes, human macrophages, tumor microenvironment",
author = "Luca Cassetta and Stamatina Fragkogianni and Sims, {Andrew H.} and Agnieszka Swierczak and Forrester, {Lesley M.} and Hui Zhang and Soong, {Daniel Y.H.} and Tiziana Cotechini and Pavana Anur and Lin, {Elaine Y.} and Antonella Fidanza and Martha Lopez-Yrigoyen and Millar, {Michael R.} and Alexandra Urman and Zhichao Ai and Spellman, {Paul T.} and Hwang, {E. Shelley} and Dixon, {J. Michael} and Lisa Wiechmann and Coussens, {Lisa M.} and Smith, {Harriet O.} and Pollard, {Jeffrey W.}",
note = "Publisher Copyright: {\textcopyright} 2019 The Authors",
year = "2019",
month = apr,
day = "15",
doi = "10.1016/j.ccell.2019.02.009",
language = "English (US)",
volume = "35",
pages = "588--602.e10",
journal = "Cancer Cell",
issn = "1535-6108",
publisher = "Cell Press",
number = "4",
}