TY - JOUR
T1 - Human papillomavirus tumour status is not associated with a positive depression screen for patients with oropharyngeal cancer
AU - Qualliotine, J. R.
AU - Califano, J. A.
AU - Li, R. J.
AU - Gold, D.
AU - Messing, B.
AU - Lee, G.
AU - Ha, P.
AU - Fakhry, C.
N1 - Publisher Copyright:
© 2017 JLO (1984) Limited.
PY - 2017/9/1
Y1 - 2017/9/1
N2 - Background: Several risk factors for depression in patients with oropharyngeal cancer have been determined. However, it is unknown whether human papillomavirus associated oropharyngeal cancer, which has a distinct clinico-demographic profile, modulates this risk. Methods: A retrospective analysis was conducted of patients with oropharyngeal cancer. These patients had completed a 10-item depression screening questionnaire before receiving treatment for their disease from 2011 to 2014. Associations between patient or disease characteristics and depression screening questionnaire results were investigated. Results: The study comprised 69 patients, 31 (44.9 per cent) of whom screened positive for depression. There were no significant differences in distributions of clinico-demographic or histopathological characteristics, including human papillomavirus tumour status, by depression screen result. Conclusion: This population has a high risk for depression, but no obvious risk factors, including human papillomavirus tumour status, were associated with an elevated risk. This inability to risk-stratify patients by clinico-demographic or disease characteristics emphasises the importance of regular depression screening for all patients in this population.
AB - Background: Several risk factors for depression in patients with oropharyngeal cancer have been determined. However, it is unknown whether human papillomavirus associated oropharyngeal cancer, which has a distinct clinico-demographic profile, modulates this risk. Methods: A retrospective analysis was conducted of patients with oropharyngeal cancer. These patients had completed a 10-item depression screening questionnaire before receiving treatment for their disease from 2011 to 2014. Associations between patient or disease characteristics and depression screening questionnaire results were investigated. Results: The study comprised 69 patients, 31 (44.9 per cent) of whom screened positive for depression. There were no significant differences in distributions of clinico-demographic or histopathological characteristics, including human papillomavirus tumour status, by depression screen result. Conclusion: This population has a high risk for depression, but no obvious risk factors, including human papillomavirus tumour status, were associated with an elevated risk. This inability to risk-stratify patients by clinico-demographic or disease characteristics emphasises the importance of regular depression screening for all patients in this population.
KW - Depression
KW - Head And Neck Cancer
KW - Oropharyngeal Neoplasms
KW - Papillomaviridae
KW - Squamous Cell Carcinoma
UR - http://www.scopus.com/inward/record.url?scp=85024478115&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85024478115&partnerID=8YFLogxK
U2 - 10.1017/S0022215117001098
DO - 10.1017/S0022215117001098
M3 - Article
C2 - 28720154
AN - SCOPUS:85024478115
SN - 0022-2151
VL - 131
SP - 760
EP - 767
JO - Journal of Laryngology and Otology
JF - Journal of Laryngology and Otology
IS - 9
ER -