Human cytomegalovirus US3 chimeras containing US2 cytosolic residues acquire major histocompatibility class I and II protein degradation properties

Agriculture & Biology

• Human betaherpesvirus 5 100%
• chimerism 76%
• protein degradation 70%
• major histocompatibility complex 49%
• degradation 36%
• endoplasmic reticulum 27%
• proteins 22%
• proteasome endopeptidase complex 21%
• adenosinetriphosphatase 16%
• glycoproteins 10%
• recombinant fusion proteins 7%
• species recruitment 5%
• cytoplasm 4%

Medicine & Life Sciences

• Histocompatibility 83%
• Cytomegalovirus 66%
• Proteolysis 62%
• Major Histocompatibility Complex 43%
• Endoplasmic Reticulum-Associated Degradation 36%
• p97 ATPase 33%
• Proteins 24%
• Proteasome Endopeptidase Complex 19%
• Hemochromatosis Protein 10%
• Glycoproteins 10%
• Membranes 7%
• Endoplasmic Reticulum 5%
• Cytoplasm 4%