How trypanosoma cruzi feasts upon its mammalian host

Nicola S. Carter; Buddy Ullman

doi:10.1016/j.chom.2013.01.003

How trypanosoma cruzi feasts upon its mammalian host

Nicola S. Carter, Buddy Ullman

Biochemistry & Molecular Biology

Research output: Contribution to journal › Short survey › peer-review

1 Scopus citations

Abstract

Trypanosoma cruzi has a complex relationship with its mammalian host in which parasite and host metabolic networks are intertwined. A genome-wide functional screen of T. cruzi infection in HeLa cells (Caradonna et al., 2013) divulges host metabolic functions and signaling pathways that impact intracellular parasite replication and reveals potential targets for therapeutic exploitation.

Original language	English (US)
Pages (from-to)	5-7
Number of pages	3
Journal	Cell Host and Microbe
Volume	13
Issue number	1
DOIs	https://doi.org/10.1016/j.chom.2013.01.003
State	Published - Jan 16 2013

ASJC Scopus subject areas

Parasitology
Microbiology
Virology

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10.1016/j.chom.2013.01.003

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title = "How trypanosoma cruzi feasts upon its mammalian host",

abstract = "Trypanosoma cruzi has a complex relationship with its mammalian host in which parasite and host metabolic networks are intertwined. A genome-wide functional screen of T. cruzi infection in HeLa cells (Caradonna et al., 2013) divulges host metabolic functions and signaling pathways that impact intracellular parasite replication and reveals potential targets for therapeutic exploitation.",

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AU - Ullman, Buddy

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AB - Trypanosoma cruzi has a complex relationship with its mammalian host in which parasite and host metabolic networks are intertwined. A genome-wide functional screen of T. cruzi infection in HeLa cells (Caradonna et al., 2013) divulges host metabolic functions and signaling pathways that impact intracellular parasite replication and reveals potential targets for therapeutic exploitation.

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How trypanosoma cruzi feasts upon its mammalian host

Abstract

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