How to assess non-calcified plaque in CT angiography: Delineation methods affect diagnostic accuracy of low-attenuation plaque by CT for lipid-core plaque in histology

Christopher L. Schlett, Maros Ferencik, Csilla Celeng, Pál Maurovich-Horvat, Hans Scheffel, Paul Stolzmann, Synho Do, Hans Ulrich Kauczor, Hatem Alkadhi, Fabian Bamberg, Udo Hoffmann

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

AimsTo compare the accuracy of two plaque delineation methods for coronary computed tomographic angiography (CTA) to identify lipid-core plaque (LCP) using histology as the reference standard.Methods and resultsFive ex vivo hearts were analysed by CTA and histology. LCP was defined by histology as fibroatheroma with core diameter/circumference >200 μm/>60° and cap thickness

Original languageEnglish (US)
Pages (from-to)1099-1105
Number of pages7
JournalEuropean Heart Journal Cardiovascular Imaging
Volume14
Issue number11
DOIs
StatePublished - Nov 2013
Externally publishedYes

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Histology
Lipids
Angiography
Atherosclerotic Plaques
Computed Tomography Angiography

Keywords

  • (Semi)-Automated plaque assessment
  • Coronary computed tomographic angiography
  • Low-attenuation plaque
  • Plaque delineation techniques

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

Cite this

How to assess non-calcified plaque in CT angiography : Delineation methods affect diagnostic accuracy of low-attenuation plaque by CT for lipid-core plaque in histology. / Schlett, Christopher L.; Ferencik, Maros; Celeng, Csilla; Maurovich-Horvat, Pál; Scheffel, Hans; Stolzmann, Paul; Do, Synho; Kauczor, Hans Ulrich; Alkadhi, Hatem; Bamberg, Fabian; Hoffmann, Udo.

In: European Heart Journal Cardiovascular Imaging, Vol. 14, No. 11, 11.2013, p. 1099-1105.

Research output: Contribution to journalArticle

Schlett, Christopher L. ; Ferencik, Maros ; Celeng, Csilla ; Maurovich-Horvat, Pál ; Scheffel, Hans ; Stolzmann, Paul ; Do, Synho ; Kauczor, Hans Ulrich ; Alkadhi, Hatem ; Bamberg, Fabian ; Hoffmann, Udo. / How to assess non-calcified plaque in CT angiography : Delineation methods affect diagnostic accuracy of low-attenuation plaque by CT for lipid-core plaque in histology. In: European Heart Journal Cardiovascular Imaging. 2013 ; Vol. 14, No. 11. pp. 1099-1105.
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