How to apply topical ocular medications

Frederick T. Fraunfelder

Research output: Contribution to journalArticlepeer-review


The most efficient way to apply topical ocular medication is to increase the volume that the 'eye' can hold by making a 'pouch' in the inferior temporal cul de sac and putting the medication in the pouch. Immediately closing the eyelids prevents the lacrimal pump from pushing the medication into the nose, thereby increasing the contact time of the drug on the anterior segment. A method to decrease systemic absorption is to keep the eyes closed for 3 minutes following the application of one drop in the pouch, and before opening the eyes, absorb with tissue as much of the medication in the inner canthus as possible. Since the 'eye' can only hold between 1/4 and 1/2 of a drop, there is no need to use more than 1 drop.

Original languageEnglish (US)
Pages (from-to)774-776
Number of pages3
JournalFolia Ophthalmologica Japonica
Issue number7
StatePublished - Sep 4 1996


  • Application
  • Eyedrops
  • Pouch
  • Recommended Method
  • Systemic Absorption

ASJC Scopus subject areas

  • Ophthalmology


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