How Psychosocial Alcohol Interventions Work: A Preliminary Look at What fMRI Can Tell Us

Sarah Feldstein Ewing, Francesca M. Filbey, Amithrupa Sabbineni, Lindsay D. Chandler, Kent E. Hutchison

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Background: Current work in motivational interviewing (MI) has supported the role of in-session client and therapist language in predicting postintervention substance use outcomes. In particular, a relationship has been found between specific therapist language (e.g., MI-consistent behaviors), specific types of client speech (e.g., change talk; CT and counterchange talk; CCT), and subsequent drinking outcomes. One hypothesis to explain this phenomenon is that CT is an indication of a neurocognitive shift that happens during the course of a psychosocial intervention. And, it is possible that this shift is responsible for catalyzing and maintaining changes in drinking behaviors following MI interventions. To investigate this question, the effect of CT on blood oxygen level-dependent (BOLD) response during the presentation of alcohol cues was evaluated using functional magnetic resonance imaging. Methods: To examine changes in neural response to alcohol cues following client language, 10 adults with alcohol dependence (50% men; 40% Caucasian; 40% Hispanic; M age=42.6; M years of education=13.3) were presented with CT and CCT derived from their prescan MI session during the presentation of alcohol cues. Results: Following CCT, there was significant neural response to alcohol cues in several key reward areas (cluster-corrected p2.3; orbitofrontal cortex, nucleus accumbens, anterior insula, posterior insula, caudate, and putamen). On the contrary, there were no areas of significant reward activation following CT. Conclusions: These results indicate that CT may be effectively inhibiting activation in brain regions that respond to the salience of alcohol cues. These findings provide preliminary biological support of the psychosocial literature findings, highlighting the critical importance of change talk during psychosocial interventions.

Original languageEnglish (US)
Pages (from-to)643-651
Number of pages9
JournalAlcoholism: Clinical and Experimental Research
Volume35
Issue number4
DOIs
StatePublished - Apr 2011
Externally publishedYes

Fingerprint

Motivational Interviewing
Cues
Alcohols
Magnetic Resonance Imaging
Language
Reward
Drinking Behavior
Chemical activation
Putamen
Nucleus Accumbens
Prefrontal Cortex
Hispanic Americans
Alcoholism
Drinking
Brain
Oxygen
Blood
Education

Keywords

  • Alcohol Dependence
  • Client Statements
  • FMRI
  • Motivational Interviewing
  • Neuroimaging

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Psychiatry and Mental health
  • Toxicology

Cite this

How Psychosocial Alcohol Interventions Work : A Preliminary Look at What fMRI Can Tell Us. / Feldstein Ewing, Sarah; Filbey, Francesca M.; Sabbineni, Amithrupa; Chandler, Lindsay D.; Hutchison, Kent E.

In: Alcoholism: Clinical and Experimental Research, Vol. 35, No. 4, 04.2011, p. 643-651.

Research output: Contribution to journalArticle

Feldstein Ewing, Sarah ; Filbey, Francesca M. ; Sabbineni, Amithrupa ; Chandler, Lindsay D. ; Hutchison, Kent E. / How Psychosocial Alcohol Interventions Work : A Preliminary Look at What fMRI Can Tell Us. In: Alcoholism: Clinical and Experimental Research. 2011 ; Vol. 35, No. 4. pp. 643-651.
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