How far to go? screening and surveillance in Barrett's esophagus

D. A. Lieberman, R. E. Sampliner

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


There is no dispute that Barrett's esophagus (BE) is associated with an increased risk of esophageal adenocarcinoma. Detecting these cancers early can improve patient survival. But should screening be used to detect BE, or should a surveillance program monitor those already diagnosed with BE for neoplastic changes? Endoscopy and endoscopic biopsy are the only tools available for such screening and surveillance, and the cost effectiveness of either approach must be considered. Two possible solutions are discussed. First, screening could be limited to patients considered at high risk for BE and associated adenocarcinoma. With this approach, more precise risk stratification would be required. The second possible approach is to combine screening for high-risk patients and surveillance for those already diagnosed with BE. Additional outcomes data are needed to determine how often and for what length of time endoscopic surveillance should continue in a patient after several examinations are negative for adenocarcinoma.

Original languageEnglish (US)
Pages (from-to)S19-S26
JournalAmerican Journal of Managed Care
Issue number1 SUPPL.
StatePublished - Mar 6 2001
Externally publishedYes

ASJC Scopus subject areas

  • Health Policy


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