How can we improve oral contraceptive success in obese women?

Ganesh Cherala, Alison Edelman

Research output: Contribution to journalReview article

Abstract

A rapid increase in obesity rates worldwide further underscores the importance of better understanding the pharmacokinetic alterations in this sub-population and the subsequent effects on pharmacotherapeutics. Pharmacokinetics of contraceptive steroids is altered in obese oral contraceptive users, which may in turn impact efficacy. Our study has identified several dosing strategies that offset these pharmacokinetic changes and may improve effectiveness for obese oral contraception users.

Original languageEnglish (US)
Pages (from-to)1-3
Number of pages3
JournalExpert Review of Clinical Pharmacology
Volume8
Issue number1
DOIs
StatePublished - Jan 1 2014

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Keywords

  • drug failure
  • obesity
  • oral contraception
  • pharmacokinetics
  • steroidal hormones

ASJC Scopus subject areas

  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Pharmacology (medical)

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