Abstract
A rapid increase in obesity rates worldwide further underscores the importance of better understanding the pharmacokinetic alterations in this sub-population and the subsequent effects on pharmacotherapeutics. Pharmacokinetics of contraceptive steroids is altered in obese oral contraceptive users, which may in turn impact efficacy. Our study has identified several dosing strategies that offset these pharmacokinetic changes and may improve effectiveness for obese oral contraception users.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1-3 |
| Number of pages | 3 |
| Journal | Expert Review of Clinical Pharmacology |
| Volume | 8 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2014 |
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Keywords
- drug failure
- obesity
- oral contraception
- pharmacokinetics
- steroidal hormones
ASJC Scopus subject areas
- Pharmacology (medical)
- Pharmacology, Toxicology and Pharmaceutics(all)
- Medicine(all)
Cite this
How can we improve oral contraceptive success in obese women? / Cherala, Ganesh; Edelman, Alison.
In: Expert Review of Clinical Pharmacology, Vol. 8, No. 1, 01.01.2014, p. 1-3.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - How can we improve oral contraceptive success in obese women?
AU - Cherala, Ganesh
AU - Edelman, Alison
PY - 2014/1/1
Y1 - 2014/1/1
N2 - A rapid increase in obesity rates worldwide further underscores the importance of better understanding the pharmacokinetic alterations in this sub-population and the subsequent effects on pharmacotherapeutics. Pharmacokinetics of contraceptive steroids is altered in obese oral contraceptive users, which may in turn impact efficacy. Our study has identified several dosing strategies that offset these pharmacokinetic changes and may improve effectiveness for obese oral contraception users.
AB - A rapid increase in obesity rates worldwide further underscores the importance of better understanding the pharmacokinetic alterations in this sub-population and the subsequent effects on pharmacotherapeutics. Pharmacokinetics of contraceptive steroids is altered in obese oral contraceptive users, which may in turn impact efficacy. Our study has identified several dosing strategies that offset these pharmacokinetic changes and may improve effectiveness for obese oral contraception users.
KW - drug failure
KW - obesity
KW - oral contraception
KW - pharmacokinetics
KW - steroidal hormones
UR - http://www.scopus.com/inward/record.url?scp=84916879356&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84916879356&partnerID=8YFLogxK
U2 - 10.1586/17512433.2015.974558
DO - 10.1586/17512433.2015.974558
M3 - Article
C2 - 25354219
AN - SCOPUS:84916879356
VL - 8
SP - 1
EP - 3
JO - Expert Review of Clinical Pharmacology
JF - Expert Review of Clinical Pharmacology
SN - 1751-2433
IS - 1
ER -