Housing characteristics, reported mold exposure, and asthma in the European Community Respiratory Health Survey

Jan Paul Zock, Deborah Jarvis, Christina Luczynska, Jordi Sunyer, Peter Burney, P. Burney, S. Chinn, C. Luczynska, D. Jarvis, E. Lai, M. Abramson, J. Kutin, P. Vermeire, F. van Bastelaer, N. Nielsen, R. Jogi, J. Bousquet, F. Neukirch, R. Liard, I. PinC. Pison, A. Taytard, H. Magnussen, D. Nowak, H. E. Wichmann, J. Heinrich, T. Gislason, D. Gislason, R. Chowgule, J. Prichard, S. Allwright, D. Mac Leod, M. Bugiani, C. Bucca, C. Romano, R. de Marco, V. Lo Cascio, C. Campello, A. Marinoni, I. Cerveri, L. Casali, B. Rijcken, A. Kremer, J. Crane, S. Lewis, A. Gulsvik, E. Omenaas, C. Svanes, J. Antó, J. Soriano, A. Tobías, J. Roca, M. Kogevinas, N. Muniozguren, J. Ramos González, A. Capelastegui, J. Martinez-Moratalla, E. Almar, J. Maldonado, A. Pereira, J. Sánchez, F. Payo, I. Huerta, G. Boman, C. Janson, E. Björnsson, L. Rosenhall, E. Norrman, B. Lundback, N. Lindholm, P. Plaschke, U. Ackermann-Liebrich, N. Künzli, A. Perruchoud, M. Burr, J. Layzqll, R. Hall, B. Harrison, J. Stark, A (Sonia) Buist, W. Vollmer, Molly Osborne

Research output: Contribution to journalArticle

190 Citations (Scopus)

Abstract

Background: The effects of home dampness and mold exposure on adult asthma are not clear. Objective: We aimed to investigate the associations between housing characteristics related to dampness, mold exposure, and house dust mite levels and adult asthma in 38 study centers from the European Community Respiratory Health Survey. Methods: Data about the present home, heating and ventilation systems, double glazing, floor covers, recent water damage, and mold exposure were obtained by means of an interviewer-led questionnaire. The associations between these factors and asthma, as defined on the basis of symptoms in the last year, and of bronchial responsiveness, as determined with methacholine challenge, were evaluated. Odds ratios (ORs) were obtained by using random-effects meta-analyses adjusted within study centers for sex, age group, and smoking status. Results: Fitted carpets and rugs in the bedroom were related to fewer asthma symptoms and bronchial responsiveness (OR range, 0.69-0.91). This effect was consistent across centers and more pronounced among house dust mite-sensitized individuals. Reported mold exposure in the last year was associated with asthma symptoms and bronchial responsiveness (OR range, 1.14-1.44). This effect was homogeneous among centers and stronger in subjects sensitized to Cladosporium species. In centers with a higher prevalence of asthma, the prevalence of reported indoor mold exposure was also high. This association was observed for reported mold exposure by asthmatic subjects (Spearman rs= 0.46), as well as reported mold exposure by nonasthmatic subjects (rs= 0.54). Reported mold exposure was highest in older houses with recent water damage. Conclusion: We conclude that indoor mold growth has an adverse effect on adult asthma.

Original languageEnglish (US)
Pages (from-to)285-292
Number of pages8
JournalJournal of Allergy and Clinical Immunology
Volume110
Issue number2
DOIs
StatePublished - 2002
Externally publishedYes

Fingerprint

European Union
Health Surveys
Fungi
Asthma
Pyroglyphidae
Odds Ratio
Cladosporium
Methacholine Chloride
Water
Heating
Ventilation
Meta-Analysis
Age Groups
Smoking
Interviews
Growth

Keywords

  • Asthma
  • Carpeting
  • Dampness
  • European Community Respiratory Health Survey
  • Housing
  • Mold

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Housing characteristics, reported mold exposure, and asthma in the European Community Respiratory Health Survey. / Zock, Jan Paul; Jarvis, Deborah; Luczynska, Christina; Sunyer, Jordi; Burney, Peter; Burney, P.; Chinn, S.; Luczynska, C.; Jarvis, D.; Lai, E.; Abramson, M.; Kutin, J.; Vermeire, P.; van Bastelaer, F.; Nielsen, N.; Jogi, R.; Bousquet, J.; Neukirch, F.; Liard, R.; Pin, I.; Pison, C.; Taytard, A.; Magnussen, H.; Nowak, D.; Wichmann, H. E.; Heinrich, J.; Gislason, T.; Gislason, D.; Chowgule, R.; Prichard, J.; Allwright, S.; Mac Leod, D.; Bugiani, M.; Bucca, C.; Romano, C.; de Marco, R.; Lo Cascio, V.; Campello, C.; Marinoni, A.; Cerveri, I.; Casali, L.; Rijcken, B.; Kremer, A.; Crane, J.; Lewis, S.; Gulsvik, A.; Omenaas, E.; Svanes, C.; Antó, J.; Soriano, J.; Tobías, A.; Roca, J.; Kogevinas, M.; Muniozguren, N.; Ramos González, J.; Capelastegui, A.; Martinez-Moratalla, J.; Almar, E.; Maldonado, J.; Pereira, A.; Sánchez, J.; Payo, F.; Huerta, I.; Boman, G.; Janson, C.; Björnsson, E.; Rosenhall, L.; Norrman, E.; Lundback, B.; Lindholm, N.; Plaschke, P.; Ackermann-Liebrich, U.; Künzli, N.; Perruchoud, A.; Burr, M.; Layzqll, J.; Hall, R.; Harrison, B.; Stark, J.; Buist, A (Sonia); Vollmer, W.; Osborne, Molly.

In: Journal of Allergy and Clinical Immunology, Vol. 110, No. 2, 2002, p. 285-292.

Research output: Contribution to journalArticle

Zock, JP, Jarvis, D, Luczynska, C, Sunyer, J, Burney, P, Burney, P, Chinn, S, Luczynska, C, Jarvis, D, Lai, E, Abramson, M, Kutin, J, Vermeire, P, van Bastelaer, F, Nielsen, N, Jogi, R, Bousquet, J, Neukirch, F, Liard, R, Pin, I, Pison, C, Taytard, A, Magnussen, H, Nowak, D, Wichmann, HE, Heinrich, J, Gislason, T, Gislason, D, Chowgule, R, Prichard, J, Allwright, S, Mac Leod, D, Bugiani, M, Bucca, C, Romano, C, de Marco, R, Lo Cascio, V, Campello, C, Marinoni, A, Cerveri, I, Casali, L, Rijcken, B, Kremer, A, Crane, J, Lewis, S, Gulsvik, A, Omenaas, E, Svanes, C, Antó, J, Soriano, J, Tobías, A, Roca, J, Kogevinas, M, Muniozguren, N, Ramos González, J, Capelastegui, A, Martinez-Moratalla, J, Almar, E, Maldonado, J, Pereira, A, Sánchez, J, Payo, F, Huerta, I, Boman, G, Janson, C, Björnsson, E, Rosenhall, L, Norrman, E, Lundback, B, Lindholm, N, Plaschke, P, Ackermann-Liebrich, U, Künzli, N, Perruchoud, A, Burr, M, Layzqll, J, Hall, R, Harrison, B, Stark, J, Buist, AS, Vollmer, W & Osborne, M 2002, 'Housing characteristics, reported mold exposure, and asthma in the European Community Respiratory Health Survey', Journal of Allergy and Clinical Immunology, vol. 110, no. 2, pp. 285-292. https://doi.org/10.1067/mai.2002.126383
Zock, Jan Paul ; Jarvis, Deborah ; Luczynska, Christina ; Sunyer, Jordi ; Burney, Peter ; Burney, P. ; Chinn, S. ; Luczynska, C. ; Jarvis, D. ; Lai, E. ; Abramson, M. ; Kutin, J. ; Vermeire, P. ; van Bastelaer, F. ; Nielsen, N. ; Jogi, R. ; Bousquet, J. ; Neukirch, F. ; Liard, R. ; Pin, I. ; Pison, C. ; Taytard, A. ; Magnussen, H. ; Nowak, D. ; Wichmann, H. E. ; Heinrich, J. ; Gislason, T. ; Gislason, D. ; Chowgule, R. ; Prichard, J. ; Allwright, S. ; Mac Leod, D. ; Bugiani, M. ; Bucca, C. ; Romano, C. ; de Marco, R. ; Lo Cascio, V. ; Campello, C. ; Marinoni, A. ; Cerveri, I. ; Casali, L. ; Rijcken, B. ; Kremer, A. ; Crane, J. ; Lewis, S. ; Gulsvik, A. ; Omenaas, E. ; Svanes, C. ; Antó, J. ; Soriano, J. ; Tobías, A. ; Roca, J. ; Kogevinas, M. ; Muniozguren, N. ; Ramos González, J. ; Capelastegui, A. ; Martinez-Moratalla, J. ; Almar, E. ; Maldonado, J. ; Pereira, A. ; Sánchez, J. ; Payo, F. ; Huerta, I. ; Boman, G. ; Janson, C. ; Björnsson, E. ; Rosenhall, L. ; Norrman, E. ; Lundback, B. ; Lindholm, N. ; Plaschke, P. ; Ackermann-Liebrich, U. ; Künzli, N. ; Perruchoud, A. ; Burr, M. ; Layzqll, J. ; Hall, R. ; Harrison, B. ; Stark, J. ; Buist, A (Sonia) ; Vollmer, W. ; Osborne, Molly. / Housing characteristics, reported mold exposure, and asthma in the European Community Respiratory Health Survey. In: Journal of Allergy and Clinical Immunology. 2002 ; Vol. 110, No. 2. pp. 285-292.
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abstract = "Background: The effects of home dampness and mold exposure on adult asthma are not clear. Objective: We aimed to investigate the associations between housing characteristics related to dampness, mold exposure, and house dust mite levels and adult asthma in 38 study centers from the European Community Respiratory Health Survey. Methods: Data about the present home, heating and ventilation systems, double glazing, floor covers, recent water damage, and mold exposure were obtained by means of an interviewer-led questionnaire. The associations between these factors and asthma, as defined on the basis of symptoms in the last year, and of bronchial responsiveness, as determined with methacholine challenge, were evaluated. Odds ratios (ORs) were obtained by using random-effects meta-analyses adjusted within study centers for sex, age group, and smoking status. Results: Fitted carpets and rugs in the bedroom were related to fewer asthma symptoms and bronchial responsiveness (OR range, 0.69-0.91). This effect was consistent across centers and more pronounced among house dust mite-sensitized individuals. Reported mold exposure in the last year was associated with asthma symptoms and bronchial responsiveness (OR range, 1.14-1.44). This effect was homogeneous among centers and stronger in subjects sensitized to Cladosporium species. In centers with a higher prevalence of asthma, the prevalence of reported indoor mold exposure was also high. This association was observed for reported mold exposure by asthmatic subjects (Spearman rs= 0.46), as well as reported mold exposure by nonasthmatic subjects (rs= 0.54). Reported mold exposure was highest in older houses with recent water damage. Conclusion: We conclude that indoor mold growth has an adverse effect on adult asthma.",
keywords = "Asthma, Carpeting, Dampness, European Community Respiratory Health Survey, Housing, Mold",
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TY - JOUR

T1 - Housing characteristics, reported mold exposure, and asthma in the European Community Respiratory Health Survey

AU - Zock, Jan Paul

AU - Jarvis, Deborah

AU - Luczynska, Christina

AU - Sunyer, Jordi

AU - Burney, Peter

AU - Burney, P.

AU - Chinn, S.

AU - Luczynska, C.

AU - Jarvis, D.

AU - Lai, E.

AU - Abramson, M.

AU - Kutin, J.

AU - Vermeire, P.

AU - van Bastelaer, F.

AU - Nielsen, N.

AU - Jogi, R.

AU - Bousquet, J.

AU - Neukirch, F.

AU - Liard, R.

AU - Pin, I.

AU - Pison, C.

AU - Taytard, A.

AU - Magnussen, H.

AU - Nowak, D.

AU - Wichmann, H. E.

AU - Heinrich, J.

AU - Gislason, T.

AU - Gislason, D.

AU - Chowgule, R.

AU - Prichard, J.

AU - Allwright, S.

AU - Mac Leod, D.

AU - Bugiani, M.

AU - Bucca, C.

AU - Romano, C.

AU - de Marco, R.

AU - Lo Cascio, V.

AU - Campello, C.

AU - Marinoni, A.

AU - Cerveri, I.

AU - Casali, L.

AU - Rijcken, B.

AU - Kremer, A.

AU - Crane, J.

AU - Lewis, S.

AU - Gulsvik, A.

AU - Omenaas, E.

AU - Svanes, C.

AU - Antó, J.

AU - Soriano, J.

AU - Tobías, A.

AU - Roca, J.

AU - Kogevinas, M.

AU - Muniozguren, N.

AU - Ramos González, J.

AU - Capelastegui, A.

AU - Martinez-Moratalla, J.

AU - Almar, E.

AU - Maldonado, J.

AU - Pereira, A.

AU - Sánchez, J.

AU - Payo, F.

AU - Huerta, I.

AU - Boman, G.

AU - Janson, C.

AU - Björnsson, E.

AU - Rosenhall, L.

AU - Norrman, E.

AU - Lundback, B.

AU - Lindholm, N.

AU - Plaschke, P.

AU - Ackermann-Liebrich, U.

AU - Künzli, N.

AU - Perruchoud, A.

AU - Burr, M.

AU - Layzqll, J.

AU - Hall, R.

AU - Harrison, B.

AU - Stark, J.

AU - Buist, A (Sonia)

AU - Vollmer, W.

AU - Osborne, Molly

PY - 2002

Y1 - 2002

N2 - Background: The effects of home dampness and mold exposure on adult asthma are not clear. Objective: We aimed to investigate the associations between housing characteristics related to dampness, mold exposure, and house dust mite levels and adult asthma in 38 study centers from the European Community Respiratory Health Survey. Methods: Data about the present home, heating and ventilation systems, double glazing, floor covers, recent water damage, and mold exposure were obtained by means of an interviewer-led questionnaire. The associations between these factors and asthma, as defined on the basis of symptoms in the last year, and of bronchial responsiveness, as determined with methacholine challenge, were evaluated. Odds ratios (ORs) were obtained by using random-effects meta-analyses adjusted within study centers for sex, age group, and smoking status. Results: Fitted carpets and rugs in the bedroom were related to fewer asthma symptoms and bronchial responsiveness (OR range, 0.69-0.91). This effect was consistent across centers and more pronounced among house dust mite-sensitized individuals. Reported mold exposure in the last year was associated with asthma symptoms and bronchial responsiveness (OR range, 1.14-1.44). This effect was homogeneous among centers and stronger in subjects sensitized to Cladosporium species. In centers with a higher prevalence of asthma, the prevalence of reported indoor mold exposure was also high. This association was observed for reported mold exposure by asthmatic subjects (Spearman rs= 0.46), as well as reported mold exposure by nonasthmatic subjects (rs= 0.54). Reported mold exposure was highest in older houses with recent water damage. Conclusion: We conclude that indoor mold growth has an adverse effect on adult asthma.

AB - Background: The effects of home dampness and mold exposure on adult asthma are not clear. Objective: We aimed to investigate the associations between housing characteristics related to dampness, mold exposure, and house dust mite levels and adult asthma in 38 study centers from the European Community Respiratory Health Survey. Methods: Data about the present home, heating and ventilation systems, double glazing, floor covers, recent water damage, and mold exposure were obtained by means of an interviewer-led questionnaire. The associations between these factors and asthma, as defined on the basis of symptoms in the last year, and of bronchial responsiveness, as determined with methacholine challenge, were evaluated. Odds ratios (ORs) were obtained by using random-effects meta-analyses adjusted within study centers for sex, age group, and smoking status. Results: Fitted carpets and rugs in the bedroom were related to fewer asthma symptoms and bronchial responsiveness (OR range, 0.69-0.91). This effect was consistent across centers and more pronounced among house dust mite-sensitized individuals. Reported mold exposure in the last year was associated with asthma symptoms and bronchial responsiveness (OR range, 1.14-1.44). This effect was homogeneous among centers and stronger in subjects sensitized to Cladosporium species. In centers with a higher prevalence of asthma, the prevalence of reported indoor mold exposure was also high. This association was observed for reported mold exposure by asthmatic subjects (Spearman rs= 0.46), as well as reported mold exposure by nonasthmatic subjects (rs= 0.54). Reported mold exposure was highest in older houses with recent water damage. Conclusion: We conclude that indoor mold growth has an adverse effect on adult asthma.

KW - Asthma

KW - Carpeting

KW - Dampness

KW - European Community Respiratory Health Survey

KW - Housing

KW - Mold

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