Host-range control of a retroviral disease: Friend erythroleukemia

M. E. Hoatlin, D. Kabat

Research output: Contribution to journalReview article

38 Scopus citations

Abstract

Since its discovery in 1957, Friend viral erythroleukemia has been the major model for understanding host genetic barriers to retroviral diseases and has facilitated the discovery of many polymorphic leukemia-control genes of mice. Some of these genes limit helper-virus replication, target-cell (erythroblast) pools or immune responses. At least one host gene appears to block the viral oncoprotein.

Original languageEnglish (US)
Pages (from-to)51-57
Number of pages7
JournalTrends in microbiology
Volume3
Issue number2
DOIs
StatePublished - Feb 1995

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases
  • Virology

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