Host-range control of a retroviral disease: Friend erythroleukemia

Maureen Hoatlin, David Kabat

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Since its discovery in 1957, Friend viral erythroleukemia has been the major model for understanding host genetic barriers to retroviral diseases and has facilitated the discovery of many polymorphic leukemia-control genes of mice. Some of these genes limit helper-virus replication, target-cell (erythroblast) pools or immune responses. At least one host gene appears to block the viral oncoprotein.

Original languageEnglish (US)
Pages (from-to)51-57
Number of pages7
JournalTrends in Microbiology
Volume3
Issue number2
DOIs
StatePublished - 1995

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Leukemia, Erythroblastic, Acute
Host Specificity
Helper Viruses
Genes
Erythroblasts
Oncogene Proteins
Virus Replication
Leukemia

ASJC Scopus subject areas

  • Microbiology
  • Virology
  • Infectious Diseases
  • Microbiology (medical)

Cite this

Host-range control of a retroviral disease : Friend erythroleukemia. / Hoatlin, Maureen; Kabat, David.

In: Trends in Microbiology, Vol. 3, No. 2, 1995, p. 51-57.

Research output: Contribution to journalArticle

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