Hormone production by cells grown in vitro on artificial capillaries

R. A. Knazek; P. O. Kohler; P. M. Gullino

doi:10.1016/0014-4827(74)90403-0

Hormone production by cells grown in vitro on artificial capillaries

R. A. Knazek, P. O. Kohler, P. M. Gullino

Research output: Contribution to journal › Article › peer-review

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Abstract

An established human choriocarcinoma cell line has been grown within a perfused artificial capillary bed. Cell densities approaching those of tissue have been attained. Cells maintained in this manner produce human chorionic gonadotropin at rates 11 times higher than those grown in conventional monolayer form.

Original language	English (US)
Pages (from-to)	251-254
Number of pages	4
Journal	Experimental Cell Research
Volume	84
Issue number	1-2
DOIs	https://doi.org/10.1016/0014-4827(74)90403-0
State	Published - Mar 15 1974
Externally published	Yes

ASJC Scopus subject areas

Cell Biology

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10.1016/0014-4827(74)90403-0

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title = "Hormone production by cells grown in vitro on artificial capillaries",

abstract = "An established human choriocarcinoma cell line has been grown within a perfused artificial capillary bed. Cell densities approaching those of tissue have been attained. Cells maintained in this manner produce human chorionic gonadotropin at rates 11 times higher than those grown in conventional monolayer form.",

author = "Knazek, {R. A.} and Kohler, {P. O.} and Gullino, {P. M.}",

note = "Funding Information: {\textquoteleft}Laboratory of Pathophysiology, National Cancer Institute, aReproduction Research Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Md 20014, USA",

year = "1974",

month = mar,

day = "15",

doi = "10.1016/0014-4827(74)90403-0",

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journal = "Experimental Cell Research",

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T1 - Hormone production by cells grown in vitro on artificial capillaries

AU - Knazek, R. A.

AU - Kohler, P. O.

AU - Gullino, P. M.

N1 - Funding Information: ‘Laboratory of Pathophysiology, National Cancer Institute, aReproduction Research Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Md 20014, USA

PY - 1974/3/15

Y1 - 1974/3/15

N2 - An established human choriocarcinoma cell line has been grown within a perfused artificial capillary bed. Cell densities approaching those of tissue have been attained. Cells maintained in this manner produce human chorionic gonadotropin at rates 11 times higher than those grown in conventional monolayer form.

AB - An established human choriocarcinoma cell line has been grown within a perfused artificial capillary bed. Cell densities approaching those of tissue have been attained. Cells maintained in this manner produce human chorionic gonadotropin at rates 11 times higher than those grown in conventional monolayer form.

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Hormone production by cells grown in vitro on artificial capillaries

Abstract

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