Histoplasmosis-like choroiditis in a nonendemic area: The northwest United States

Robert C. Watzke, Michael L. Klein, Mark H. Wener

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Purpose: Histoplasmosis is not endemic in the U.S. northwest, but a type of multifocal choroiditis resembling ocular histoplasmosis occurs there. This study was designed to find a group of affected patients and study their clinical characteristics and immunologic responses to Histoplasma antigens. Method: Ten patients were found in the authors' files whose geographic histories made it unlikely that they had ever been exposed to Histoplasma capsulatum and yet they had features of ocular histoplasmosis. They were recalled for examination and testing by lymphocyte-stimulation assay for previous exposure to histoplasmosis. Results: The clinical features of these patients resembled those of patients with ocular histoplasmosis, but their histories and the results of the assay did not support H. capsulatum as the cause of the ocular disease. Conclusion: This study confirmed that there is a type of choroiditis that resembles ocular histoplasmosis but is due to another agent or agents.

Original languageEnglish (US)
Pages (from-to)204-212
Number of pages9
Issue number3
StatePublished - Jan 1 1998


  • Histoplasmosis
  • Multifocal choroiditis
  • Ocular histoplasmosis

ASJC Scopus subject areas

  • Ophthalmology


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