Histochemical localization of carbonic anhydrase in the inner ear

David J. Lim, Christos Karabinas, Dennis Trune

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Carbonic anhydrase was histochemically located in chinchilla inner ear tissues. A strong carbonic anhydrase reaction was observed in the spiral ligament cells, Boettcher's cells, the external sulcus cells, and the stria vascularis (intermediate and/or basal cells). The enzymatic reaction was also positive in the supporting cells of all vestibular sensory epithelia, as well as in the dark cells and transitional cells of the utricle and saccule. Some epithelial cells of the endolymphatic sac were also positive. It is speculated that this enzyme may be involved in: 1) ionic or fluid regulation of the endolymph, 2) removal of CO2 from the inner ear tissue near the sensory cells, and 3) otoconia formation and maintenance.

Original languageEnglish (US)
Pages (from-to)33-42
Number of pages10
JournalAmerican Journal of Otolaryngology--Head and Neck Medicine and Surgery
Volume4
Issue number1
DOIs
StatePublished - Jan 2 1983
Externally publishedYes

Fingerprint

Carbonic Anhydrases
Inner Ear
Spiral Ligament of Cochlea
Endolymph
Endolymphatic Sac
Chinchilla
Stria Vascularis
Saccule and Utricle
Otolithic Membrane
Epithelium
Epithelial Cells
Maintenance
Enzymes

Keywords

  • Carbonic anhydrase
  • Chinchilla
  • Histochemistry
  • Inner ear

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Histochemical localization of carbonic anhydrase in the inner ear. / Lim, David J.; Karabinas, Christos; Trune, Dennis.

In: American Journal of Otolaryngology--Head and Neck Medicine and Surgery, Vol. 4, No. 1, 02.01.1983, p. 33-42.

Research output: Contribution to journalArticle

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