High concentrations of oxytocin in hypophysial portal plasma

D. M. Gibbs

Research output: Contribution to journalArticle

108 Citations (Scopus)

Abstract

Hypophysial portal blood was collected from pentobarbital-anesthetized male rats, and the content of oxytocin (OT) was measured by RIA. The concentration of OT in portal plasma was 1.88 ± 0.48 ng/ml (SEM) and was at least 15 times higher than the concentration of OT in peripheral plasma samples from the same rats. Dilutions of portal plasma produced a displacement curve parallel to those of synthetic OT and posterior lobe extract. The data support a possible role for OT as a hypothalamic-releasing hormone.

Original languageEnglish (US)
Pages (from-to)1216-1218
Number of pages3
JournalEndocrinology
Volume114
Issue number4
StatePublished - 1984

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Oxytocin
Pituitary Hormone-Releasing Hormones
Pentobarbital

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

High concentrations of oxytocin in hypophysial portal plasma. / Gibbs, D. M.

In: Endocrinology, Vol. 114, No. 4, 1984, p. 1216-1218.

Research output: Contribution to journalArticle

Gibbs, DM 1984, 'High concentrations of oxytocin in hypophysial portal plasma', Endocrinology, vol. 114, no. 4, pp. 1216-1218.
Gibbs, D. M. / High concentrations of oxytocin in hypophysial portal plasma. In: Endocrinology. 1984 ; Vol. 114, No. 4. pp. 1216-1218.
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