Heterogeneity of hematopoietic stem cells

Nobuko Uchida, William Fleming, Eytan J. Alpern, Irving L. Weissman

Research output: Contribution to journalArticle

105 Citations (Scopus)

Abstract

Hematopoietic stem cells are capable of multi-lineage differentiation to all blood cell types as well as self-renewal and radioprotection. Thy-1.1lo Lin-/lo Sca-1+ cells are a heterogeneous mixture of quiescent and self-renewing hematopoietic stem cells as well as multi-lineage expanding cells.

Original languageEnglish (US)
Pages (from-to)177-184
Number of pages8
JournalCurrent Opinion in Immunology
Volume5
Issue number2
DOIs
StatePublished - 1993
Externally publishedYes

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Hematopoietic Stem Cells
Blood Cells

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

Cite this

Heterogeneity of hematopoietic stem cells. / Uchida, Nobuko; Fleming, William; Alpern, Eytan J.; Weissman, Irving L.

In: Current Opinion in Immunology, Vol. 5, No. 2, 1993, p. 177-184.

Research output: Contribution to journalArticle

Uchida, Nobuko ; Fleming, William ; Alpern, Eytan J. ; Weissman, Irving L. / Heterogeneity of hematopoietic stem cells. In: Current Opinion in Immunology. 1993 ; Vol. 5, No. 2. pp. 177-184.
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