Heptavalent pneumococcal conjugate vaccine immunogenicity in very-low-birth-weight, premature infants

Carl T. D'Angio, Roy J. Heyne, T. Michael O'Shea, Robert Schelonka, Seetha Shankaran, Shahnaz Duara, Ronald N. Goldberg, Barbara J. Stoll, Krisa P. Van Meurs, Betty R. Vohr, Abhik Das, Lei Li, Robert L. Burton, Betty Hastings, Dale L. Phelps, Pablo J. Sanchez, Waldemar A. Carlo, David K. Stevenson, Rosemary D. Higgins

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Background: The heptavalent pneumococcal CRM197 conjugate vaccine (PCV-7) has been incompletely studied in very-low-birth-weight (≤1500 g) infants. Objective: To assess PCV-7 immunogenicity in very-low-birth-weight, premature infants. We hypothesized that the frequency of postvaccine antibody concentrations 0.15 μg/mL would vary directly with birth weight. Methods: This was a multicenter observational study. Infants 401 to 1500 g birth weight and

Original languageEnglish (US)
Pages (from-to)600-606
Number of pages7
JournalPediatric Infectious Disease Journal
Volume29
Issue number7
DOIs
StatePublished - Jul 2010
Externally publishedYes

Fingerprint

Very Low Birth Weight Infant
Birth Weight
Premature Infants
Multicenter Studies
Observational Studies
Antibodies
Vaccine Immunogenicity
Heptavalent Pneumococcal Conjugate Vaccine
CRM197 (non-toxic variant of diphtheria toxin)

Keywords

  • immunization
  • pneumococcal vaccines
  • premature infant
  • vaccines
  • very low birth weight infant

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Infectious Diseases
  • Microbiology (medical)
  • Medicine(all)

Cite this

Heptavalent pneumococcal conjugate vaccine immunogenicity in very-low-birth-weight, premature infants. / D'Angio, Carl T.; Heyne, Roy J.; O'Shea, T. Michael; Schelonka, Robert; Shankaran, Seetha; Duara, Shahnaz; Goldberg, Ronald N.; Stoll, Barbara J.; Van Meurs, Krisa P.; Vohr, Betty R.; Das, Abhik; Li, Lei; Burton, Robert L.; Hastings, Betty; Phelps, Dale L.; Sanchez, Pablo J.; Carlo, Waldemar A.; Stevenson, David K.; Higgins, Rosemary D.

In: Pediatric Infectious Disease Journal, Vol. 29, No. 7, 07.2010, p. 600-606.

Research output: Contribution to journalArticle

D'Angio, CT, Heyne, RJ, O'Shea, TM, Schelonka, R, Shankaran, S, Duara, S, Goldberg, RN, Stoll, BJ, Van Meurs, KP, Vohr, BR, Das, A, Li, L, Burton, RL, Hastings, B, Phelps, DL, Sanchez, PJ, Carlo, WA, Stevenson, DK & Higgins, RD 2010, 'Heptavalent pneumococcal conjugate vaccine immunogenicity in very-low-birth-weight, premature infants', Pediatric Infectious Disease Journal, vol. 29, no. 7, pp. 600-606. https://doi.org/10.1097/INF.0b013e3181d264a6
D'Angio, Carl T. ; Heyne, Roy J. ; O'Shea, T. Michael ; Schelonka, Robert ; Shankaran, Seetha ; Duara, Shahnaz ; Goldberg, Ronald N. ; Stoll, Barbara J. ; Van Meurs, Krisa P. ; Vohr, Betty R. ; Das, Abhik ; Li, Lei ; Burton, Robert L. ; Hastings, Betty ; Phelps, Dale L. ; Sanchez, Pablo J. ; Carlo, Waldemar A. ; Stevenson, David K. ; Higgins, Rosemary D. / Heptavalent pneumococcal conjugate vaccine immunogenicity in very-low-birth-weight, premature infants. In: Pediatric Infectious Disease Journal. 2010 ; Vol. 29, No. 7. pp. 600-606.
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