Hepatosplenomegaly and reticulocytopenia as prominent features of atypical hemolytic uremic syndrome

Kirsten Bechtel, Sandra Iragorri

Research output: Contribution to journalArticle

2 Scopus citations


This is a case of atypical hemolytic uremic syndrome (HUS) due to invasive pneumococcal disease in which the prominent clinical features were reticulocytopenia and hepatosplenomegaly, leading to the incorrect initial diagnosis of acute leukemia. Delayed diagnosis of HUS, especially in atypical cases, can lead to increased morbidity and mortality. Atypical HUS must be part of the differential diagnosis of children who present with clinical characteristics suggestive of a hematologic malignancy with associated renal injury.

Original languageEnglish (US)
Pages (from-to)510-511
Number of pages2
JournalPediatric emergency care
Issue number7
StatePublished - Jul 2010



  • hemolytic uremic syndrome
  • hepatosplenomegaly
  • invasive pneumococcal disease
  • reticulocytopenia

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Emergency Medicine

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