Hepatitis D virus: A call to screening

Joseph Ahn, Robert G. Gish

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Hepatitis D virus causes an aggressive viral hepatitis with a virulent course of progression to cirrhosis and hepatic decompensation. It relies on hepatitis B coinfection for its pathogenesis and propagation. Hepatitis D virus had become the forgotten virus, with reduced public awareness, medical interest, and research support. Recently, there has been a resurgence of awareness and interest in hepatitis D, with improvements in diagnostic testing and establishment of international collaborative efforts to improve therapy. This article provides a framework to understand the impetus for increased screening as well as to identify key issues toward which collaborative efforts can be directed.

Original languageEnglish (US)
Pages (from-to)647-686
Number of pages40
JournalGastroenterology and Hepatology
Volume10
Issue number10
StatePublished - Oct 1 2014

Keywords

  • Cirrhosis
  • Hepatitis delta
  • Interferon
  • Pegylated interferon
  • Prenylation inhibitors

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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