Hepatitis c-associated cryoglobulinemic glomerulonephritis with crystalline deposits

Mazdak A. Khalighi, Charles R. Lassman

Research output: Contribution to journalArticle

Abstract

Infection with hepatitis C virus has been associated with a number of extrahepatic manifestations, including kidney disease. Of the glomerular pathologic states described with hepatitis C virus infection, cryoglobulinemic glomerulonephritis is the most prevalent. On kidney biopsy, cryoglobulinemic glomerulonephritis has a variable appearance, with a membranoproliferative pattern of injury as the most common light microscopic finding. Ultrastructurally, curved and paired microtubules are the most characteristic finding, but these also can be variable. We present a case of cryoglobulinemic glomerulonephritis with distinct and highly unusual ultrastructural findings.

Original languageEnglish (US)
Pages (from-to)384-389
Number of pages6
JournalAmerican Journal of Kidney Diseases
Volume62
Issue number2
DOIs
StatePublished - Aug 1 2013

Keywords

  • Cryoglobulinemia
  • cryoglobulinemic glomerulonephritis
  • crystalline deposits
  • hepatitis C
  • membranoproliferative glomerulonephritis
  • organized deposits

ASJC Scopus subject areas

  • Nephrology

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