TY - JOUR
T1 - Hemodynamic effects of 1:2 ECG-coupled jet ventilation in the dog
T2 - A comparison with other modes
AU - Schulman, D. S.
AU - Biondi, J. W.
AU - Bell, L.
AU - Rutlen, D. L.
PY - 1991
Y1 - 1991
N2 - In 16 closed-chest dogs the hemodynamics of ECG-coupled jet ventilation (JV) with frequencies of 1:1 (one breath for each cardiac systole) and 1:2 (one breath for every other cardiac systole) were compared to noncoupled JV and intermittent positive-pressure ventilation (IPPV). Cardiac output was similar during 1:2 coupling (1.6 ± 0.2 L/min) and IPPV (1.6 ± 0.2 L/min) but decreased during 1:1 coupling (1.2 ± 0.2 L/min) and noncoupled JV (1.3 ± 0.2 L/min), p < 0.05. During 1:2 coupling and IPPV, systemic arterial and transmural left atrial pressures were increased, and pulmonary artery, pericardial, and right atrial pressures were decreased in comparison to the other JV modes. Pulmonary blood volume was preserved during 1:2 coupling but decreased during 1:1 coupling and noncoupled JV. Coupling at 1:2 preserves output by maintaining left ventricular preload via a decrease in right atrial pressure and subsequent maintenance of systemic venous return.
AB - In 16 closed-chest dogs the hemodynamics of ECG-coupled jet ventilation (JV) with frequencies of 1:1 (one breath for each cardiac systole) and 1:2 (one breath for every other cardiac systole) were compared to noncoupled JV and intermittent positive-pressure ventilation (IPPV). Cardiac output was similar during 1:2 coupling (1.6 ± 0.2 L/min) and IPPV (1.6 ± 0.2 L/min) but decreased during 1:1 coupling (1.2 ± 0.2 L/min) and noncoupled JV (1.3 ± 0.2 L/min), p < 0.05. During 1:2 coupling and IPPV, systemic arterial and transmural left atrial pressures were increased, and pulmonary artery, pericardial, and right atrial pressures were decreased in comparison to the other JV modes. Pulmonary blood volume was preserved during 1:2 coupling but decreased during 1:1 coupling and noncoupled JV. Coupling at 1:2 preserves output by maintaining left ventricular preload via a decrease in right atrial pressure and subsequent maintenance of systemic venous return.
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U2 - 10.1164/ajrccm/144.4.819
DO - 10.1164/ajrccm/144.4.819
M3 - Article
C2 - 1928955
AN - SCOPUS:0026012349
SN - 0003-0805
VL - 144
SP - 819
EP - 825
JO - American Review of Respiratory Disease
JF - American Review of Respiratory Disease
IS - 4
ER -