Hemodynamic and hormonal responses to hemorrhage in conscious rabbits at mid- and late gestation

Virginia Brooks, Rebecca R. Quesnell, Colleen M. Kane, Lanny C. Keil

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

This study tests the hypothesis that conscious rabbits late in pregnancy (P), but not at midgestation (MP), are less able to maintain arterial pressure during hemorrhage. Blood volume (BV) was elevated (P <0.05) by an average of 13 ± 4 (MP) and 35 ± 3% (P). Rabbits were bled in both the nonpregnant (NP) and P state at 2% of the initial BV per minute. The hemorrhage was stopped after arterial pressure decreased. In NP rabbits, arterial pressure was well maintained near control pressures of 70 ± 2 mmHg until 38 ± 2% of the initial BV was removed and then rapidly fell to reach a nadir at 35 ± 2 mmHg. In contrast, in P rabbits, basal arterial pressure was lower (61 ± 2 mmHg; P <0.05) and gradually decreased to below control after

Original languageEnglish (US)
JournalAmerican Journal of Physiology - Regulatory Integrative and Comparative Physiology
Volume275
Issue number4 44-4
StatePublished - Oct 1998

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Arterial Pressure
Blood Volume
Hemodynamics
Hemorrhage
Rabbits
Pregnancy
Pressure

Keywords

  • Angiotensin II
  • Arterial pressure
  • Baroreceptor reflex
  • Heart rate
  • Renin
  • Vasopressin

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)

Cite this

Hemodynamic and hormonal responses to hemorrhage in conscious rabbits at mid- and late gestation. / Brooks, Virginia; Quesnell, Rebecca R.; Kane, Colleen M.; Keil, Lanny C.

In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology, Vol. 275, No. 4 44-4, 10.1998.

Research output: Contribution to journalArticle

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