Hematologic reactions to carbonic anhydrase inhibitors

F. T. Fraunfelder; S. M. Meyer; G. C. Bagby; M. W. Dreis

doi:10.1016/S0002-9394(14)74987-6

Hematologic reactions to carbonic anhydrase inhibitors

F. T. Fraunfelder, S. M. Meyer, G. C. Bagby, M. W. Dreis

Ophthalmology

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

The National Registry of Drug-Induced Ocular Side effects has received 79 cases reports of suspected hematopoietic toxicity caused by carbonic anhydrase inhibitors. Twenty-six of these suspected cases (32%) resulted in death secondary to aplastic anemia, thrombocytopenia, or granulocytosis. In 54 of these 79, adverse reactions (68% occurred during the first six months of therapy).

Original language	English (US)
Pages (from-to)	79-81
Number of pages	3
Journal	American journal of ophthalmology
Volume	100
Issue number	1
DOIs	https://doi.org/10.1016/S0002-9394(14)74987-6
State	Published - Jan 1 1985

ASJC Scopus subject areas

Ophthalmology

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title = "Hematologic reactions to carbonic anhydrase inhibitors",

abstract = "The National Registry of Drug-Induced Ocular Side effects has received 79 cases reports of suspected hematopoietic toxicity caused by carbonic anhydrase inhibitors. Twenty-six of these suspected cases (32%) resulted in death secondary to aplastic anemia, thrombocytopenia, or granulocytosis. In 54 of these 79, adverse reactions (68% occurred during the first six months of therapy).",

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AU - Meyer, S. M.

AU - Bagby, G. C.

AU - Dreis, M. W.

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N2 - The National Registry of Drug-Induced Ocular Side effects has received 79 cases reports of suspected hematopoietic toxicity caused by carbonic anhydrase inhibitors. Twenty-six of these suspected cases (32%) resulted in death secondary to aplastic anemia, thrombocytopenia, or granulocytosis. In 54 of these 79, adverse reactions (68% occurred during the first six months of therapy).

AB - The National Registry of Drug-Induced Ocular Side effects has received 79 cases reports of suspected hematopoietic toxicity caused by carbonic anhydrase inhibitors. Twenty-six of these suspected cases (32%) resulted in death secondary to aplastic anemia, thrombocytopenia, or granulocytosis. In 54 of these 79, adverse reactions (68% occurred during the first six months of therapy).

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