Hearing preservation after stereotactic radiosurgery for vestibular schwannoma

A systematic review

Isaac Yang, Derrick Aranda, Seunggu (Jude) Han, Sravana Chennupati, Michael E. Sughrue, Steven W. Cheung, Lawrence H. Pitts, Andrew T. Parsa

Research output: Contribution to journalReview article

73 Citations (Scopus)

Abstract

Radiosurgery has evolved into an effective alternative to microsurgical resection in the treatment of patients with vestibular schwannoma. We performed a systematic analysis of the literature in English on the radiosurgical treatment of vestibular schwannoma patients. A total of 254 published studies reported assessable and quantifiable outcome data of patients undergoing radiosurgery for vestibular schwannomas. American Association of Otolaryngology-Head and Neck Surgery (AAO-HNS) class A or B and Gardner-Robertson (GR) classification I or II were defined as having preserved hearing. A total of 5825 patients (74 articles) met our inclusion criteria. Practitioners who delivered an average dose of ≤12.5 Gy as the marginal dose reported having a higher hearing preservation rate (≤12.5 Gy = 59% vs. >12.5 Gy = 53%, p = 0.0285). Age of the patient was not a significant prognostic factor for hearing preservation rates (<65 years = 58% vs. >65 years = 62%; p = 0.4317). The average overall follow-up was 41.2 months. Our data suggest that an overall hearing preservation rate of about 57% can be expected after radiosurgical treatment, and patients treated with ≤12.5 Gy were more likely to have preserved hearing.

Original languageEnglish (US)
Pages (from-to)742-747
Number of pages6
JournalJournal of Clinical Neuroscience
Volume16
Issue number6
DOIs
StatePublished - Jun 1 2009
Externally publishedYes

Fingerprint

Acoustic Neuroma
Radiosurgery
Hearing
Otolaryngology
Neck
Therapeutics
Head

Keywords

  • Gamma knife
  • Hearing preservation
  • Linac
  • Proton beam
  • Radiosurgery
  • Stereotactic radiosurgery
  • Vestibular schwannoma

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Physiology (medical)

Cite this

Hearing preservation after stereotactic radiosurgery for vestibular schwannoma : A systematic review. / Yang, Isaac; Aranda, Derrick; Han, Seunggu (Jude); Chennupati, Sravana; Sughrue, Michael E.; Cheung, Steven W.; Pitts, Lawrence H.; Parsa, Andrew T.

In: Journal of Clinical Neuroscience, Vol. 16, No. 6, 01.06.2009, p. 742-747.

Research output: Contribution to journalReview article

Yang, I, Aranda, D, Han, SJ, Chennupati, S, Sughrue, ME, Cheung, SW, Pitts, LH & Parsa, AT 2009, 'Hearing preservation after stereotactic radiosurgery for vestibular schwannoma: A systematic review', Journal of Clinical Neuroscience, vol. 16, no. 6, pp. 742-747. https://doi.org/10.1016/j.jocn.2008.09.023
Yang, Isaac ; Aranda, Derrick ; Han, Seunggu (Jude) ; Chennupati, Sravana ; Sughrue, Michael E. ; Cheung, Steven W. ; Pitts, Lawrence H. ; Parsa, Andrew T. / Hearing preservation after stereotactic radiosurgery for vestibular schwannoma : A systematic review. In: Journal of Clinical Neuroscience. 2009 ; Vol. 16, No. 6. pp. 742-747.
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