Health-related quality of life for children with ASD: Associations with behavioral characteristics

Karen Kuhlthau; Erica Kovacs; Trevor Hall; Traci Clemmons; Felice Orlich; Jennifer Delahaye; Darryn Sikora

doi:10.1016/j.rasd.2013.04.006

Health-related quality of life for children with ASD: Associations with behavioral characteristics

Karen Kuhlthau, Erica Kovacs, Trevor Hall, Traci Clemmons, Felice Orlich, Jennifer Delahaye, Darryn Sikora

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

This paper examines health-related quality of life (HRQoL) of children age 6-11 years with an autism spectrum disorder (ASD) using the Child Health and Illness Profile - Child Edition (CHIP-CE). We further examine associations of HRQoL scores with measures of behavior using regression models. Overall HRQoL scores are lower than those for normative samples. We find that both externalizing and internalizing behaviors (measured with the Child Behavior Checklist) are correlated with HRQoL as are several of the subscales of the aberrant behavior checklist. These results suggest that some potentially modifiable aspects of ASD, in particular ASD-related and aberrant behaviors, are associated with HRQoL. These associations are suggestive of the potential for improvements in behaviors in some domains having the potential to improve HRQoL. Future studies should determine whether improvements in behaviors are associated with improvements in HRQoL.

Original language	English (US)
Pages (from-to)	1035-1042
Number of pages	8
Journal	Research in Autism Spectrum Disorders
Volume	7
Issue number	9
DOIs	https://doi.org/10.1016/j.rasd.2013.04.006
State	Published - 2013
Externally published	Yes

Keywords

Behavior
Health-related quality of life

ASJC Scopus subject areas

Developmental and Educational Psychology
Clinical Psychology
Psychiatry and Mental health

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10.1016/j.rasd.2013.04.006

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@article{6ef208641ec7438085fb62ec670524c0,

title = "Health-related quality of life for children with ASD: Associations with behavioral characteristics",

abstract = "This paper examines health-related quality of life (HRQoL) of children age 6-11 years with an autism spectrum disorder (ASD) using the Child Health and Illness Profile - Child Edition (CHIP-CE). We further examine associations of HRQoL scores with measures of behavior using regression models. Overall HRQoL scores are lower than those for normative samples. We find that both externalizing and internalizing behaviors (measured with the Child Behavior Checklist) are correlated with HRQoL as are several of the subscales of the aberrant behavior checklist. These results suggest that some potentially modifiable aspects of ASD, in particular ASD-related and aberrant behaviors, are associated with HRQoL. These associations are suggestive of the potential for improvements in behaviors in some domains having the potential to improve HRQoL. Future studies should determine whether improvements in behaviors are associated with improvements in HRQoL.",

keywords = "Behavior, Health-related quality of life",

author = "Karen Kuhlthau and Erica Kovacs and Trevor Hall and Traci Clemmons and Felice Orlich and Jennifer Delahaye and Darryn Sikora",

note = "Funding Information: We acknowledge the funding support of the Autism Speaks Foundation and the Nancy Lurie Marks Family Foundation. The content is solely the responsibility of the authors and does not necessarily represent the official views of the funders. The authors acknowledge the members of the Autism Treatment Network (ATN) for assisting in recruiting respondents. Some of the data used in this study was collected as a part of the ATN, a program of Autism Speaks. Further support came from a cooperative agreement (UA3 MC 11054) from the US Department of Health and Human Services, Health Resources and Services Administration, Maternal and Child Health Research Program to the Massachusetts General Hospital. We further thank our project consultants, Dr. Riley, Dr. Landgraf, and Dr. Varni along with the families who agreed to be interviewed as a part of this study.",

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doi = "10.1016/j.rasd.2013.04.006",

language = "English (US)",

volume = "7",

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T2 - Associations with behavioral characteristics

AU - Kuhlthau, Karen

AU - Kovacs, Erica

AU - Hall, Trevor

AU - Clemmons, Traci

AU - Orlich, Felice

AU - Delahaye, Jennifer

AU - Sikora, Darryn

N1 - Funding Information: We acknowledge the funding support of the Autism Speaks Foundation and the Nancy Lurie Marks Family Foundation. The content is solely the responsibility of the authors and does not necessarily represent the official views of the funders. The authors acknowledge the members of the Autism Treatment Network (ATN) for assisting in recruiting respondents. Some of the data used in this study was collected as a part of the ATN, a program of Autism Speaks. Further support came from a cooperative agreement (UA3 MC 11054) from the US Department of Health and Human Services, Health Resources and Services Administration, Maternal and Child Health Research Program to the Massachusetts General Hospital. We further thank our project consultants, Dr. Riley, Dr. Landgraf, and Dr. Varni along with the families who agreed to be interviewed as a part of this study.

PY - 2013

Y1 - 2013

N2 - This paper examines health-related quality of life (HRQoL) of children age 6-11 years with an autism spectrum disorder (ASD) using the Child Health and Illness Profile - Child Edition (CHIP-CE). We further examine associations of HRQoL scores with measures of behavior using regression models. Overall HRQoL scores are lower than those for normative samples. We find that both externalizing and internalizing behaviors (measured with the Child Behavior Checklist) are correlated with HRQoL as are several of the subscales of the aberrant behavior checklist. These results suggest that some potentially modifiable aspects of ASD, in particular ASD-related and aberrant behaviors, are associated with HRQoL. These associations are suggestive of the potential for improvements in behaviors in some domains having the potential to improve HRQoL. Future studies should determine whether improvements in behaviors are associated with improvements in HRQoL.

AB - This paper examines health-related quality of life (HRQoL) of children age 6-11 years with an autism spectrum disorder (ASD) using the Child Health and Illness Profile - Child Edition (CHIP-CE). We further examine associations of HRQoL scores with measures of behavior using regression models. Overall HRQoL scores are lower than those for normative samples. We find that both externalizing and internalizing behaviors (measured with the Child Behavior Checklist) are correlated with HRQoL as are several of the subscales of the aberrant behavior checklist. These results suggest that some potentially modifiable aspects of ASD, in particular ASD-related and aberrant behaviors, are associated with HRQoL. These associations are suggestive of the potential for improvements in behaviors in some domains having the potential to improve HRQoL. Future studies should determine whether improvements in behaviors are associated with improvements in HRQoL.

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Health-related quality of life for children with ASD: Associations with behavioral characteristics

Abstract

Keywords

ASJC Scopus subject areas

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