Growth and growth hormone in Turner syndrome: Looking back, looking ahead

Evan Los, Ron G. Rosenfeld

Research output: Contribution to journalReview article

1 Scopus citations

Abstract

Short stature is the most ubiquitous feature of Turner syndrome (TS). Today, many girls with TS are treated with recombinant human growth hormone (GH) to accelerate growth in childhood and to improve adult height. Here, we will review the history of our understanding of growth in TS, reflect on the path of clinical trials ultimately leading to regulatory approval for clinical use of GH, discuss factors associated with growth outcomes and survey the current unanswered questions about growth and GH in TS.

Original languageEnglish (US)
Pages (from-to)86-90
Number of pages5
JournalAmerican Journal of Medical Genetics, Part C: Seminars in Medical Genetics
Volume181
Issue number1
DOIs
StatePublished - Mar 2019

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Keywords

  • Turner syndrome
  • growth
  • growth hormone

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

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