Group index of the human cornea at 1.3-μm wavelength obtained in vitro by optical coherence domain reflectometry

Roger C. Lin, Mark A. Shure, Andrew M. Rollins, Joseph A. Izatt, David Huang

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

The group index of the cornea, rather than the phase refractive index, is required for thickness calculations with optical coherence tomography. Recent advances with high-speed optical coherence tomography at 1.3 μm make index measurement at this wavelength of great interest. Group indices of three human corneas from an eye bank were measured in vitro with optical coherence domain reflectometry. Measurements were made in a calibrated cuvette filled with a preservation medium to maintain proper corneal hydration. Group indices were calculated from the optical path lengths measured. The corneal group index was 1.389 ± 0.004 (average ± standard deviation). The average group index of a balanced salt solution, an approximation to aqueous humor, was 1.343 ± 0.001.

Original languageEnglish (US)
Pages (from-to)83-85
Number of pages3
JournalOptics Letters
Volume29
Issue number1
DOIs
StatePublished - Jan 1 2004
Externally publishedYes

Fingerprint

cornea
wavelengths
tomography
optical paths
hydration
standard deviation
high speed
refractivity
salts
approximation

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Group index of the human cornea at 1.3-μm wavelength obtained in vitro by optical coherence domain reflectometry. / Lin, Roger C.; Shure, Mark A.; Rollins, Andrew M.; Izatt, Joseph A.; Huang, David.

In: Optics Letters, Vol. 29, No. 1, 01.01.2004, p. 83-85.

Research output: Contribution to journalArticle

Lin, Roger C. ; Shure, Mark A. ; Rollins, Andrew M. ; Izatt, Joseph A. ; Huang, David. / Group index of the human cornea at 1.3-μm wavelength obtained in vitro by optical coherence domain reflectometry. In: Optics Letters. 2004 ; Vol. 29, No. 1. pp. 83-85.
@article{a0d0894edf50431ab366c58f18efd813,
title = "Group index of the human cornea at 1.3-μm wavelength obtained in vitro by optical coherence domain reflectometry",
abstract = "The group index of the cornea, rather than the phase refractive index, is required for thickness calculations with optical coherence tomography. Recent advances with high-speed optical coherence tomography at 1.3 μm make index measurement at this wavelength of great interest. Group indices of three human corneas from an eye bank were measured in vitro with optical coherence domain reflectometry. Measurements were made in a calibrated cuvette filled with a preservation medium to maintain proper corneal hydration. Group indices were calculated from the optical path lengths measured. The corneal group index was 1.389 ± 0.004 (average ± standard deviation). The average group index of a balanced salt solution, an approximation to aqueous humor, was 1.343 ± 0.001.",
author = "Lin, {Roger C.} and Shure, {Mark A.} and Rollins, {Andrew M.} and Izatt, {Joseph A.} and David Huang",
year = "2004",
month = "1",
day = "1",
doi = "10.1364/OL.29.000083",
language = "English (US)",
volume = "29",
pages = "83--85",
journal = "Optics Letters",
issn = "0146-9592",
publisher = "The Optical Society",
number = "1",

}

TY - JOUR

T1 - Group index of the human cornea at 1.3-μm wavelength obtained in vitro by optical coherence domain reflectometry

AU - Lin, Roger C.

AU - Shure, Mark A.

AU - Rollins, Andrew M.

AU - Izatt, Joseph A.

AU - Huang, David

PY - 2004/1/1

Y1 - 2004/1/1

N2 - The group index of the cornea, rather than the phase refractive index, is required for thickness calculations with optical coherence tomography. Recent advances with high-speed optical coherence tomography at 1.3 μm make index measurement at this wavelength of great interest. Group indices of three human corneas from an eye bank were measured in vitro with optical coherence domain reflectometry. Measurements were made in a calibrated cuvette filled with a preservation medium to maintain proper corneal hydration. Group indices were calculated from the optical path lengths measured. The corneal group index was 1.389 ± 0.004 (average ± standard deviation). The average group index of a balanced salt solution, an approximation to aqueous humor, was 1.343 ± 0.001.

AB - The group index of the cornea, rather than the phase refractive index, is required for thickness calculations with optical coherence tomography. Recent advances with high-speed optical coherence tomography at 1.3 μm make index measurement at this wavelength of great interest. Group indices of three human corneas from an eye bank were measured in vitro with optical coherence domain reflectometry. Measurements were made in a calibrated cuvette filled with a preservation medium to maintain proper corneal hydration. Group indices were calculated from the optical path lengths measured. The corneal group index was 1.389 ± 0.004 (average ± standard deviation). The average group index of a balanced salt solution, an approximation to aqueous humor, was 1.343 ± 0.001.

UR - http://www.scopus.com/inward/record.url?scp=0347764650&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0347764650&partnerID=8YFLogxK

U2 - 10.1364/OL.29.000083

DO - 10.1364/OL.29.000083

M3 - Article

C2 - 14719668

AN - SCOPUS:0347764650

VL - 29

SP - 83

EP - 85

JO - Optics Letters

JF - Optics Letters

SN - 0146-9592

IS - 1

ER -