Group B streptococcus: Prevalence in a non-obstetric population

Catherine M. Leclair, Ashley E. Hart, Martha F. Goetsch, Heather Carpentier, Jeffrey T. Jensen

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Objective.: To establish and compare the prevalence of group B streptococcus (GBS) colonization in the vaginas of nonobstetric women with and without vaginitis. Materials and methods.: Cross-sectional analysis GBS vaginal culture status of nonpregnant, estrogen-replete women 18 years or older presenting for annual gynecological examinations or vaginal infection. Subjects were classified into 3 groups: no vaginitis if symptoms were absent and examination results was normal; common vaginitis (CV) if microscopic examination revealed yeast, bacterial vaginosis, or trichomonads; or inflammatory vaginitis (IV) if examination revealed inflammation and immature squamous cells but no pathogens. Results.: Of the 215 women recruited, 147 (68.4%) showed no evidence of vaginitis, 41 (19.1%) had CV, and 27 (12.6%) showed evidence of IV. The overall prevalence rate of GBS was 22.8%. Vaginitis was associated with a significantly increased risk of GBS colonization (adjusted odds ratio: CV = 2.7, 95% CI = 1.1-6.2; IV = 2.9, 95% CI = 1.1-8.0). Logistic regression revealed pH higher than 4.5, presence of abnormal discharge on examination, and a women's complaint of current symptoms as significant predicators of the presence of GBS. Conclusions.: Group B streptococcus colonization occurs more commonly in women with vaginitis. This suggests that disruption of the normal vaginal bacterial environment is an important predictor for GBS colonization.

Original languageEnglish (US)
Pages (from-to)162-166
Number of pages5
JournalJournal of lower genital tract disease
Volume14
Issue number3
DOIs
StatePublished - Jul 1 2010

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Keywords

  • Streptococcus agalactiae
  • group B streptococcus
  • prevalence
  • vagina
  • vaginitis

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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