Gestational weight loss and perinatal outcomes in overweight and obese women subsequent to diagnosis of gestational diabetes mellitus

Lynn M. Yee, Yvonne W. Cheng, Maribeth Inturrisi, Aaron Caughey

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objective To investigate whether gestational weight loss (GWL) after the diagnosis of gestational diabetes mellitus (GDM) in overweight and obese women is associated with improved perinatal outcomes. Obesity and GDM are risk factors for adverse perinatal outcomes, but few studies have investigated weight loss during pregnancy in women with these comorbidities. Design and Methods Retrospective cohort study of 26,205 overweight and obese gestational diabetic women enrolled in the California Diabetes and Pregnancy Program. Women with GWL during program enrollment were compared to those with weight gain. Perinatal outcomes were assessed using chi-square test and multivariable logistic regression analysis. Results About 5.2% of women experienced GWL. GWL was associated with decreased odds of macrosomia (aOR 0.63, 95% CI 0.52-0.77), NICU admission (aOR 0.51, 95% CI 0.27-0.95), and cesarean delivery (aOR 0.81, 95% CI 0.68-0.97). Odds of SGA status (aOR 1.69, 95% CI 1.32-2.17) and preterm delivery

Original languageEnglish (US)
JournalObesity
Volume21
Issue number12
DOIs
StatePublished - Dec 2013

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Gestational Diabetes
Weight Loss
Weight Reduction Programs
Pregnancy in Diabetics
Chi-Square Distribution
Weight Gain
Comorbidity
Cohort Studies
Retrospective Studies
Obesity
Logistic Models
Regression Analysis
Outcome Assessment (Health Care)
Pregnancy

ASJC Scopus subject areas

  • Endocrinology
  • Medicine (miscellaneous)
  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics

Cite this

Gestational weight loss and perinatal outcomes in overweight and obese women subsequent to diagnosis of gestational diabetes mellitus. / Yee, Lynn M.; Cheng, Yvonne W.; Inturrisi, Maribeth; Caughey, Aaron.

In: Obesity, Vol. 21, No. 12, 12.2013.

Research output: Contribution to journalArticle

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