Genetic disruption of the Sh3pxd2a gene reveals an essential role in mouse development and the existence of a novel isoform of Tks5

Agriculture & Biology

• essential genes 96%
• gene targeting 93%
• exons 79%
• mice 50%
• cell movement 47%
• fibroblasts 38%
• genes 30%
• neural crest 29%
• scaffolding proteins 29%
• palate 28%
• degradation 26%
• molecular weight 26%
• transcription initiation site 25%
• proteasome endopeptidase complex 25%
• start codon 24%
• phosphatidylinositols 23%
• expressed sequence tags 23%
• Danio rerio 22%
• introns 18%
• phosphotransferases (kinases) 18%
• traps 18%
• neonates 18%
• death 16%
• mutants 12%
• extracts 11%
• tissues 9%
• proteins 7%

Medicine & Life Sciences

• Essential Genes 100%
• Protein Isoforms 71%
• Exons 58%
• Genes 35%
• phosphatidylinositol 3,4-diphosphate 29%
• Molecular Weight 29%
• Cell Movement 28%
• Podosomes 26%
• Fibroblasts 26%
• Expressed Sequence Tags 22%
• Initiator Codon 21%
• src-Family Kinases 20%
• Transcription Initiation Site 20%
• Neural Crest 20%
• Perinatal Death 20%
• Cleft Palate 19%
• Proteasome Endopeptidase Complex 18%
• Zebrafish 17%
• Introns 16%
• Proteins 12%
• Messenger RNA 10%

Chemical Compounds

• Weight 46%
• Tyrosine 40%
• Protein 36%