Genetic analysis workshop II: Further consideration of segregation and linkage analyses in problem 3

P. L. Kramer, D. B. Altmann, K. K. Kidd

Research output: Contribution to journalArticle

Abstract

We analyzed disease-marker association in Problem 3 for the Genetic Analysis Workshop II, using PAP for segregation analysis and LIPED for linkage analysis. Certain features that we added to the running of LIPED to facilitate the analyses are discussed. Furthermore, we tested for Mendelian transmission in the hypothetical trait locus and we calculated modified relative risks for marker-trait genotypes. Some of the problems involved in analyzing complex associations among loci are discussed.

Original languageEnglish (US)
Pages (from-to)189-193
Number of pages5
JournalGenetic Epidemiology
Volume1
Issue number2
StatePublished - 1984
Externally publishedYes

Fingerprint

Genotype
Education

ASJC Scopus subject areas

  • Epidemiology
  • Genetics(clinical)

Cite this

Genetic analysis workshop II : Further consideration of segregation and linkage analyses in problem 3. / Kramer, P. L.; Altmann, D. B.; Kidd, K. K.

In: Genetic Epidemiology, Vol. 1, No. 2, 1984, p. 189-193.

Research output: Contribution to journalArticle

Kramer, P. L. ; Altmann, D. B. ; Kidd, K. K. / Genetic analysis workshop II : Further consideration of segregation and linkage analyses in problem 3. In: Genetic Epidemiology. 1984 ; Vol. 1, No. 2. pp. 189-193.
@article{d38e47df59084c22890bc5dbf8a8d74b,
title = "Genetic analysis workshop II: Further consideration of segregation and linkage analyses in problem 3",
abstract = "We analyzed disease-marker association in Problem 3 for the Genetic Analysis Workshop II, using PAP for segregation analysis and LIPED for linkage analysis. Certain features that we added to the running of LIPED to facilitate the analyses are discussed. Furthermore, we tested for Mendelian transmission in the hypothetical trait locus and we calculated modified relative risks for marker-trait genotypes. Some of the problems involved in analyzing complex associations among loci are discussed.",
author = "Kramer, {P. L.} and Altmann, {D. B.} and Kidd, {K. K.}",
year = "1984",
language = "English (US)",
volume = "1",
pages = "189--193",
journal = "Genetic Epidemiology",
issn = "0741-0395",
publisher = "Wiley-Liss Inc.",
number = "2",

}

TY - JOUR

T1 - Genetic analysis workshop II

T2 - Further consideration of segregation and linkage analyses in problem 3

AU - Kramer, P. L.

AU - Altmann, D. B.

AU - Kidd, K. K.

PY - 1984

Y1 - 1984

N2 - We analyzed disease-marker association in Problem 3 for the Genetic Analysis Workshop II, using PAP for segregation analysis and LIPED for linkage analysis. Certain features that we added to the running of LIPED to facilitate the analyses are discussed. Furthermore, we tested for Mendelian transmission in the hypothetical trait locus and we calculated modified relative risks for marker-trait genotypes. Some of the problems involved in analyzing complex associations among loci are discussed.

AB - We analyzed disease-marker association in Problem 3 for the Genetic Analysis Workshop II, using PAP for segregation analysis and LIPED for linkage analysis. Certain features that we added to the running of LIPED to facilitate the analyses are discussed. Furthermore, we tested for Mendelian transmission in the hypothetical trait locus and we calculated modified relative risks for marker-trait genotypes. Some of the problems involved in analyzing complex associations among loci are discussed.

UR - http://www.scopus.com/inward/record.url?scp=0021671344&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021671344&partnerID=8YFLogxK

M3 - Article

C2 - 14971372

AN - SCOPUS:0021671344

VL - 1

SP - 189

EP - 193

JO - Genetic Epidemiology

JF - Genetic Epidemiology

SN - 0741-0395

IS - 2

ER -