Genetic analysis of a Chinese hamster cell line lacking a G1 phase

R. Michael Liskay

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

A Chinese hamster cell line (V79-8), which lacks a measurable G1 phase in its cell cycle (G1-), has been investigated utilizing somatic cell hybrids. The results indicate that the G1- phenotype is dominant in two types of intraspecific hybrids and, surprisingly is in contrast recessive in two different interspecific crosses. Furthermore, the G1- V79-8 cell line complements two different G1 defective cell cycle mutants, suggesting that V79-8 retains and can express at least some G1-specific functions.

Original languageEnglish (US)
Pages (from-to)69-77
Number of pages9
JournalExperimental Cell Research
Volume114
Issue number1
DOIs
StatePublished - Jun 1978

ASJC Scopus subject areas

  • Cell Biology

Fingerprint Dive into the research topics of 'Genetic analysis of a Chinese hamster cell line lacking a G1 phase'. Together they form a unique fingerprint.

  • Cite this