Genetic analysis of a Chinese hamster cell line lacking a G1 phase

Robert (Mike) Liskay

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

A Chinese hamster cell line (V79-8), which lacks a measurable G1 phase in its cell cycle (G1-), has been investigated utilizing somatic cell hybrids. The results indicate that the G1- phenotype is dominant in two types of intraspecific hybrids and, surprisingly is in contrast recessive in two different interspecific crosses. Furthermore, the G1- V79-8 cell line complements two different G1 defective cell cycle mutants, suggesting that V79-8 retains and can express at least some G1-specific functions.

Original languageEnglish (US)
Pages (from-to)69-77
Number of pages9
JournalExperimental Cell Research
Volume114
Issue number1
DOIs
StatePublished - 1978
Externally publishedYes

Fingerprint

G1 Phase
Cricetulus
Cell Cycle
Cell Line
Hybrid Cells
Phenotype

ASJC Scopus subject areas

  • Cell Biology

Cite this

Genetic analysis of a Chinese hamster cell line lacking a G1 phase. / Liskay, Robert (Mike).

In: Experimental Cell Research, Vol. 114, No. 1, 1978, p. 69-77.

Research output: Contribution to journalArticle

Liskay, Robert (Mike). / Genetic analysis of a Chinese hamster cell line lacking a G1 phase. In: Experimental Cell Research. 1978 ; Vol. 114, No. 1. pp. 69-77.
@article{5b7481c037664c919f1bc54bd84a572d,
title = "Genetic analysis of a Chinese hamster cell line lacking a G1 phase",
abstract = "A Chinese hamster cell line (V79-8), which lacks a measurable G1 phase in its cell cycle (G1-), has been investigated utilizing somatic cell hybrids. The results indicate that the G1- phenotype is dominant in two types of intraspecific hybrids and, surprisingly is in contrast recessive in two different interspecific crosses. Furthermore, the G1- V79-8 cell line complements two different G1 defective cell cycle mutants, suggesting that V79-8 retains and can express at least some G1-specific functions.",
author = "Liskay, {Robert (Mike)}",
year = "1978",
doi = "10.1016/0014-4827(78)90037-X",
language = "English (US)",
volume = "114",
pages = "69--77",
journal = "Experimental Cell Research",
issn = "0014-4827",
publisher = "Academic Press Inc.",
number = "1",

}

TY - JOUR

T1 - Genetic analysis of a Chinese hamster cell line lacking a G1 phase

AU - Liskay, Robert (Mike)

PY - 1978

Y1 - 1978

N2 - A Chinese hamster cell line (V79-8), which lacks a measurable G1 phase in its cell cycle (G1-), has been investigated utilizing somatic cell hybrids. The results indicate that the G1- phenotype is dominant in two types of intraspecific hybrids and, surprisingly is in contrast recessive in two different interspecific crosses. Furthermore, the G1- V79-8 cell line complements two different G1 defective cell cycle mutants, suggesting that V79-8 retains and can express at least some G1-specific functions.

AB - A Chinese hamster cell line (V79-8), which lacks a measurable G1 phase in its cell cycle (G1-), has been investigated utilizing somatic cell hybrids. The results indicate that the G1- phenotype is dominant in two types of intraspecific hybrids and, surprisingly is in contrast recessive in two different interspecific crosses. Furthermore, the G1- V79-8 cell line complements two different G1 defective cell cycle mutants, suggesting that V79-8 retains and can express at least some G1-specific functions.

UR - http://www.scopus.com/inward/record.url?scp=0018100085&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018100085&partnerID=8YFLogxK

U2 - 10.1016/0014-4827(78)90037-X

DO - 10.1016/0014-4827(78)90037-X

M3 - Article

C2 - 658159

AN - SCOPUS:0018100085

VL - 114

SP - 69

EP - 77

JO - Experimental Cell Research

JF - Experimental Cell Research

SN - 0014-4827

IS - 1

ER -