Gender differences in cerebellar metabolism

Test-retest reproducibility

Nora D. Volkow, Gene Jack Wang, Joanna S. Fowler, Robert Hitzemann, Naomi Pappas, Kathleen Pascani, Christopher Wong

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

Objective: The purpose of this study was to evaluate gender differences in baseline measures of regional brain metabolism and to assess their reproducibility. Method: Fifteen male and 13 female healthy subjects, whose mean age was 44 years, were tested with positron emission tomography and [18F]fluorodeoxyglucose (FDG) under resting conditions; eight of the men and 11 of the women underwent a second FDG scan under the same conditions 4- 6 weeks later to assess the reproducibility of the previous results. Results: There were no differences in whole brain metabolism between the women and the men. In the first evaluation the female subjects showed significantly higher metabolism in the temporal poles and cerebellum than the male subjects. During the second evaluation the female subjects had significantly higher metabolism only in the cerebellum. Conclusions: This study documents significant and reproducible gender differences in cerebellar metabolism; their functional significance merits further evaluation.

Original languageEnglish (US)
Pages (from-to)119-121
Number of pages3
JournalAmerican Journal of Psychiatry
Volume154
Issue number1
StatePublished - 1997
Externally publishedYes

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Cerebellum
Fluorodeoxyglucose F18
Brain
Reproducibility of Results
Positron-Emission Tomography
Healthy Volunteers

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Volkow, N. D., Wang, G. J., Fowler, J. S., Hitzemann, R., Pappas, N., Pascani, K., & Wong, C. (1997). Gender differences in cerebellar metabolism: Test-retest reproducibility. American Journal of Psychiatry, 154(1), 119-121.

Gender differences in cerebellar metabolism : Test-retest reproducibility. / Volkow, Nora D.; Wang, Gene Jack; Fowler, Joanna S.; Hitzemann, Robert; Pappas, Naomi; Pascani, Kathleen; Wong, Christopher.

In: American Journal of Psychiatry, Vol. 154, No. 1, 1997, p. 119-121.

Research output: Contribution to journalArticle

Volkow, ND, Wang, GJ, Fowler, JS, Hitzemann, R, Pappas, N, Pascani, K & Wong, C 1997, 'Gender differences in cerebellar metabolism: Test-retest reproducibility', American Journal of Psychiatry, vol. 154, no. 1, pp. 119-121.
Volkow ND, Wang GJ, Fowler JS, Hitzemann R, Pappas N, Pascani K et al. Gender differences in cerebellar metabolism: Test-retest reproducibility. American Journal of Psychiatry. 1997;154(1):119-121.
Volkow, Nora D. ; Wang, Gene Jack ; Fowler, Joanna S. ; Hitzemann, Robert ; Pappas, Naomi ; Pascani, Kathleen ; Wong, Christopher. / Gender differences in cerebellar metabolism : Test-retest reproducibility. In: American Journal of Psychiatry. 1997 ; Vol. 154, No. 1. pp. 119-121.
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