Gender-based differences in mortality in response to high product ratio massive transfusion

Susan Rowell, Ronald R. Barbosa, Carrie E. Allison, Philbert Van, Martin Schreiber, Trauma Outcomes Group The Trauma Outcomes Group

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    22 Scopus citations

    Abstract

    Background: Recent data suggest that patients undergoing massive transfusion have lower mortality rates when ratios of plasma and platelets to red blood cells (RBCs) of ≥1:2 are used. This has not been examined independently in women and men. A gender dichotomy in outcome after severe injury is known to exist. This study examined gender-related differences in mortality after high product ratio massive transfusion. Methods: A retrospective study was conducted using a database containing massively transfused trauma patients from 23 Level I trauma centers. Baseline demographic, physiologic, and biochemical data were obtained. Univariate and logistic regression analyses were performed. Adjusted mortality in patients receiving high (≥1:2) or low (

    Original languageEnglish (US)
    JournalJournal of Trauma - Injury, Infection and Critical Care
    Volume71
    Issue number2 SUPPL. 3
    DOIs
    Publication statusPublished - Aug 2011

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    Keywords

    • Gender
    • Massive transfusion
    • Mortality
    • Trauma

    ASJC Scopus subject areas

    • Surgery
    • Critical Care and Intensive Care Medicine

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