Gastrointestinal dysfunction in Parkinson's disease

Ronald F. Pfeiffer

Research output: Contribution to journalReview articlepeer-review

225 Scopus citations

Abstract

In recent years, an increasingly detailed picture of gastrointestinal dysfunction in the setting of Parkinson's disease has emerged. Abnormalities of function may occur at virtually all levels of the gastrointestinal tract. Weight loss, dental deterioration, salivary excess, dysphagia, gastroparesis, decreased bowel movement frequency, and anorectal dysfunction all may occur. The pathophysiologic basis for this dysfunction entails both central and enteric nervous system involvement.

Original languageEnglish (US)
Pages (from-to)10-15
Number of pages6
JournalParkinsonism and Related Disorders
Volume17
Issue number1
DOIs
StatePublished - Jan 2011
Externally publishedYes

Keywords

  • Anorectal dysfunction
  • Constipation
  • Dysphagia
  • Gastrointestinal dysfunction
  • Gastroparesis
  • Parkinson's disease

ASJC Scopus subject areas

  • Neurology
  • Geriatrics and Gerontology
  • Clinical Neurology

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