TY - JOUR
T1 - Gastric linitis plastica with metastases to the colon
T2 - A mimic of crohn's disease
AU - Katon, Ronald M.
AU - Brendler, Sarah J.
AU - Ireland, Karen
PY - 1989/10
Y1 - 1989/10
N2 - A 60-year-old woman had progressive lower abdominal pain, nonbloody diarrhea, and weight loss, followed by severe epigastric pain and dysphagia. Radiographic evaluation of the colon showed segmental strictures which were interpreted as Crohn's disease. Medical treatment was not helpful. Neither gross endoscopic appearance nor multiple biopsies of the esophagus, stomach, and colon were diagnostic. Finally, laparotomy with full-thickness biopsies of the stomach and colon revealed linitis plastica. The clinician should be alert to colonic metastases from gastric linitis plastica, for it can produce focal or segmental strictures, mimicking more common colonic diseases such as Crohn's disease. A full-thickness biopsy is often necessary for a firm diagnosis. We review the literature on this occurrence, highlighting the clinical and radiologic spectrum, as well as the organ systems most often affected when gastric linitis plastica metastasizes.
AB - A 60-year-old woman had progressive lower abdominal pain, nonbloody diarrhea, and weight loss, followed by severe epigastric pain and dysphagia. Radiographic evaluation of the colon showed segmental strictures which were interpreted as Crohn's disease. Medical treatment was not helpful. Neither gross endoscopic appearance nor multiple biopsies of the esophagus, stomach, and colon were diagnostic. Finally, laparotomy with full-thickness biopsies of the stomach and colon revealed linitis plastica. The clinician should be alert to colonic metastases from gastric linitis plastica, for it can produce focal or segmental strictures, mimicking more common colonic diseases such as Crohn's disease. A full-thickness biopsy is often necessary for a firm diagnosis. We review the literature on this occurrence, highlighting the clinical and radiologic spectrum, as well as the organ systems most often affected when gastric linitis plastica metastasizes.
KW - Colonic metastases
KW - Laparotomy
KW - Linitis plastica
UR - http://www.scopus.com/inward/record.url?scp=0024443115&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0024443115&partnerID=8YFLogxK
U2 - 10.1097/00004836-198910000-00013
DO - 10.1097/00004836-198910000-00013
M3 - Article
C2 - 2551955
AN - SCOPUS:0024443115
SN - 0192-0790
VL - 11
SP - 555
EP - 560
JO - Journal of clinical gastroenterology
JF - Journal of clinical gastroenterology
IS - 5
ER -