Gastric cancer: Standards for the 21st century

Victor Archie, John Kauh, Dennie V. Jones, Victor Cruz, Martin S. Karpeh, Charles R. Thomas

Research output: Contribution to journalReview article

22 Scopus citations

Abstract

Although the incidence of gastric cancer has been decreasing in the United States, it remains a leading cause of cancer death in the world, only lung cancer causes more deaths worldwide. The combination of relatively low prevalence, lack of pathognomonic symptoms, and lack of defined risk factors are associated with a delay in diagnosis leading to a dismal prognosis. For localized disease, surgery remains a cornerstone of treatment but much controversy remains regarding optimal peri-operative therapy. For advanced disease, several new agents and new combination chemotherapies have offered encouraging results. This paper seeks to review the major topics surrounding gastric cancer and cover the results of recently reported and ongoing trials.

Original languageEnglish (US)
Pages (from-to)123-131
Number of pages9
JournalCritical Reviews in Oncology/Hematology
Volume57
Issue number2
DOIs
StatePublished - Feb 1 2006

Keywords

  • Adenocarcinoma
  • Chemotherapy
  • Combined modality
  • Radiation therapy
  • Staging
  • Stomach cancer
  • Surgery

ASJC Scopus subject areas

  • Hematology
  • Oncology

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