Garlic I: More than just bad breath: Fatal Forty DDI: Garlic, ritonavir, CYP3A4, P-glycoprotein

Vincent Lew; Kirk Lalwani

doi:10.1007/978-1-4614-7495-1_215

Garlic I: More than just bad breath: Fatal Forty DDI: Garlic, ritonavir, CYP3A4, P-glycoprotein

Vincent Lew, Kirk Lalwani

Anesthesiology and Perioperative Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This case discusses a pharmacokinetic interaction between ritonavir and garlic resulting in abdominal distress. Ritonavir is a cytochrome P450 3A4 and/or P-glycoprotein substrate and garlic is a 3A4 and/or P-glycoprotein inhibitor.

Original language	English (US)
Title of host publication	A Case Approach to Perioperative Drug-Drug Interactions
Publisher	Springer New York
Pages	953-955
Number of pages	3
ISBN (Electronic)	9781461474951
ISBN (Print)	9781461474944
DOIs	https://doi.org/10.1007/978-1-4614-7495-1_215
State	Published - Sep 15 2015

ASJC Scopus subject areas

General Medicine

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10.1007/978-1-4614-7495-1_215

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abstract = "This case discusses a pharmacokinetic interaction between ritonavir and garlic resulting in abdominal distress. Ritonavir is a cytochrome P450 3A4 and/or P-glycoprotein substrate and garlic is a 3A4 and/or P-glycoprotein inhibitor.",

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Garlic I: More than just bad breath: Fatal Forty DDI: Garlic, ritonavir, CYP3A4, P-glycoprotein

Abstract

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