Gallbladder dynamics induced by a fatty meal in normal subjects and patients with gallstones

Concise communication

V. R. Bobba, G. T. Krishnamurthy, E. Kingston, F. E. Turner, Paul Brown, K. Langrell

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

A study was undertaken to establish the pattern of gallbladder emptying in normal subjects and in patients with gallstones, using a fatty meal as stimulus to release endogenous cholecystokinin. The time from meal ingestion to beginning of gallbladder emptying (latent period), the total duration of emptying (ejection period), degree of emptying (ejection fraction), and the rate of emptying (ejection fraction/ejection period) were measured noninvasively by a nongeometric scintigraphic technique. The mean latent period and ejection rate were similar in normal subjects and patients with gallstones, but the mean ejection period and ejection fraction were significantly reduced in the patients. This study suggests that for an identical stimulus, the gallbladder in cholelithiasis begins to empty at the normal time but empties for a shorter duration; the result is a reduction of ejection fraction but not of ejection rate.

Original languageEnglish (US)
Pages (from-to)21-24
Number of pages4
JournalJournal of Nuclear Medicine
Volume25
Issue number1
StatePublished - 1984
Externally publishedYes

Fingerprint

Gallstones
Gallbladder
Gallbladder Emptying
Meals
Communication
Cholelithiasis
Cholecystokinin
Eating

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Bobba, V. R., Krishnamurthy, G. T., Kingston, E., Turner, F. E., Brown, P., & Langrell, K. (1984). Gallbladder dynamics induced by a fatty meal in normal subjects and patients with gallstones: Concise communication. Journal of Nuclear Medicine, 25(1), 21-24.

Gallbladder dynamics induced by a fatty meal in normal subjects and patients with gallstones : Concise communication. / Bobba, V. R.; Krishnamurthy, G. T.; Kingston, E.; Turner, F. E.; Brown, Paul; Langrell, K.

In: Journal of Nuclear Medicine, Vol. 25, No. 1, 1984, p. 21-24.

Research output: Contribution to journalArticle

Bobba, VR, Krishnamurthy, GT, Kingston, E, Turner, FE, Brown, P & Langrell, K 1984, 'Gallbladder dynamics induced by a fatty meal in normal subjects and patients with gallstones: Concise communication', Journal of Nuclear Medicine, vol. 25, no. 1, pp. 21-24.
Bobba, V. R. ; Krishnamurthy, G. T. ; Kingston, E. ; Turner, F. E. ; Brown, Paul ; Langrell, K. / Gallbladder dynamics induced by a fatty meal in normal subjects and patients with gallstones : Concise communication. In: Journal of Nuclear Medicine. 1984 ; Vol. 25, No. 1. pp. 21-24.
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