Galanin message-associated peptide suppresses growth and the budded-to-hyphal-form transition of Candida albicans

Isabella Rauch; Linda Lundström; Markus Hell; Wolfgang Sperl; Barbara Kofler

doi:10.1128/AAC.00166-07

Galanin message-associated peptide suppresses growth and the budded-to-hyphal-form transition of Candida albicans

Isabella Rauch, Linda Lundström, Markus Hell, Wolfgang Sperl, Barbara Kofler

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

The expression of the mRNA encoding galanin message-associated peptide (GMAP) in human keratinocytes is upregulated by lipopolysaccharides and exposure to Candida albicans. GMAP has growth-inhibiting activity against C. albicans and inhibits the budded-to-hyphal-form transition, establishing GMAP as a possible new component of the innate immune system.

Original language	English (US)
Pages (from-to)	4167-4170
Number of pages	4
Journal	Antimicrobial agents and chemotherapy
Volume	51
Issue number	11
DOIs	https://doi.org/10.1128/AAC.00166-07
State	Published - Nov 2007
Externally published	Yes

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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10.1128/AAC.00166-07

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title = "Galanin message-associated peptide suppresses growth and the budded-to-hyphal-form transition of Candida albicans",

abstract = "The expression of the mRNA encoding galanin message-associated peptide (GMAP) in human keratinocytes is upregulated by lipopolysaccharides and exposure to Candida albicans. GMAP has growth-inhibiting activity against C. albicans and inhibits the budded-to-hyphal-form transition, establishing GMAP as a possible new component of the innate immune system.",

author = "Isabella Rauch and Linda Lundstr{\"o}m and Markus Hell and Wolfgang Sperl and Barbara Kofler",

year = "2007",

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doi = "10.1128/AAC.00166-07",

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T1 - Galanin message-associated peptide suppresses growth and the budded-to-hyphal-form transition of Candida albicans

AU - Rauch, Isabella

AU - Lundström, Linda

AU - Hell, Markus

AU - Sperl, Wolfgang

AU - Kofler, Barbara

PY - 2007/11

Y1 - 2007/11

N2 - The expression of the mRNA encoding galanin message-associated peptide (GMAP) in human keratinocytes is upregulated by lipopolysaccharides and exposure to Candida albicans. GMAP has growth-inhibiting activity against C. albicans and inhibits the budded-to-hyphal-form transition, establishing GMAP as a possible new component of the innate immune system.

AB - The expression of the mRNA encoding galanin message-associated peptide (GMAP) in human keratinocytes is upregulated by lipopolysaccharides and exposure to Candida albicans. GMAP has growth-inhibiting activity against C. albicans and inhibits the budded-to-hyphal-form transition, establishing GMAP as a possible new component of the innate immune system.

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U2 - 10.1128/AAC.00166-07

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AN - SCOPUS:35848935884

SN - 0066-4804

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JO - Antimicrobial agents and chemotherapy

JF - Antimicrobial agents and chemotherapy

IS - 11

ER -

Galanin message-associated peptide suppresses growth and the budded-to-hyphal-form transition of Candida albicans

Abstract

ASJC Scopus subject areas

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