Galanin message-associated peptide suppresses growth and the budded-to-hyphal-form transition of Candida albicans

Isabella Rauch, Linda Lundström, Markus Hell, Wolfgang Sperl, Barbara Kofler

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

The expression of the mRNA encoding galanin message-associated peptide (GMAP) in human keratinocytes is upregulated by lipopolysaccharides and exposure to Candida albicans. GMAP has growth-inhibiting activity against C. albicans and inhibits the budded-to-hyphal-form transition, establishing GMAP as a possible new component of the innate immune system.

Original languageEnglish (US)
Pages (from-to)4167-4170
Number of pages4
JournalAntimicrobial agents and chemotherapy
Volume51
Issue number11
DOIs
StatePublished - Nov 1 2007

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ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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