Galanin message-associated peptide suppresses growth and the budded-to-hyphal-form transition of Candida albicans

Isabella Rauch, Linda Lundström, Markus Hell, Wolfgang Sperl, Barbara Kofler

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The expression of the mRNA encoding galanin message-associated peptide (GMAP) in human keratinocytes is upregulated by lipopolysaccharides and exposure to Candida albicans. GMAP has growth-inhibiting activity against C. albicans and inhibits the budded-to-hyphal-form transition, establishing GMAP as a possible new component of the innate immune system.

Original languageEnglish (US)
Pages (from-to)4167-4170
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume51
Issue number11
DOIs
StatePublished - Nov 1 2007
Externally publishedYes

Fingerprint

Candida albicans
Growth
Keratinocytes
Lipopolysaccharides
Immune System
Messenger RNA
galanin message-associated peptide

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

Cite this

Galanin message-associated peptide suppresses growth and the budded-to-hyphal-form transition of Candida albicans. / Rauch, Isabella; Lundström, Linda; Hell, Markus; Sperl, Wolfgang; Kofler, Barbara.

In: Antimicrobial Agents and Chemotherapy, Vol. 51, No. 11, 01.11.2007, p. 4167-4170.

Research output: Contribution to journalArticle

Rauch, Isabella ; Lundström, Linda ; Hell, Markus ; Sperl, Wolfgang ; Kofler, Barbara. / Galanin message-associated peptide suppresses growth and the budded-to-hyphal-form transition of Candida albicans. In: Antimicrobial Agents and Chemotherapy. 2007 ; Vol. 51, No. 11. pp. 4167-4170.
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