Gadolinium-DTPA-enhanced magnetic resonance imaging of musculoskeletal infectious processes

Katharine Hopkins, King C P Li, Gabrielle Bergman

Research output: Contribution to journalArticle

120 Citations (Scopus)

Abstract

The purpose of this study was to assess whether gadolinium-enhanced magnetic resonance imaging (MRI) provides diagnostic information beyond that given by nonenhanced imaging in the evaluation of musculoskeletal infectious processes and whether it can be used for differentiating infectious from noninfectious inflammatory lesions. Magnetic resonance images performed with and without intravenous gadolinium-DTPA in 34 cases in which musculoskeletal infection had been clinically suspected were reviewed. Infectious lesionsincluding osteomyelitis, pyarthrosis, abscess, and cellulitis-were confirmed in a total of 22 cases: in 15 by biopsy or drainage and in 7 by clinical course. Our results show that gadolinium-DTPA-enhanced MRI is a highly sensitive technique in diagnosing musculoskeletal infectious lesions. It is especially useful in distinguishing abscesses from surrounding cellulitis/myositis. Lack of contrast enhancement rules out infection with a high degree of certainty. However, contrast enhancement cannot be used to reliably distinguish infectious from noninfectious inflammatory conditions.

Original languageEnglish (US)
Pages (from-to)325-330
Number of pages6
JournalSkeletal Radiology
Volume24
Issue number5
DOIs
StatePublished - Jul 1995
Externally publishedYes

Fingerprint

Gadolinium DTPA
Cellulitis
Abscess
Magnetic Resonance Imaging
Myositis
Gadolinium
Osteomyelitis
Infection
Drainage
Magnetic Resonance Spectroscopy
Biopsy

Keywords

  • Contrast enhancement
  • Infection
  • Magnetic resonance
  • Musculoskeletal

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

Cite this

Gadolinium-DTPA-enhanced magnetic resonance imaging of musculoskeletal infectious processes. / Hopkins, Katharine; Li, King C P; Bergman, Gabrielle.

In: Skeletal Radiology, Vol. 24, No. 5, 07.1995, p. 325-330.

Research output: Contribution to journalArticle

@article{bba636048f68427ebf1ef9f54e4a5b01,
title = "Gadolinium-DTPA-enhanced magnetic resonance imaging of musculoskeletal infectious processes",
abstract = "The purpose of this study was to assess whether gadolinium-enhanced magnetic resonance imaging (MRI) provides diagnostic information beyond that given by nonenhanced imaging in the evaluation of musculoskeletal infectious processes and whether it can be used for differentiating infectious from noninfectious inflammatory lesions. Magnetic resonance images performed with and without intravenous gadolinium-DTPA in 34 cases in which musculoskeletal infection had been clinically suspected were reviewed. Infectious lesionsincluding osteomyelitis, pyarthrosis, abscess, and cellulitis-were confirmed in a total of 22 cases: in 15 by biopsy or drainage and in 7 by clinical course. Our results show that gadolinium-DTPA-enhanced MRI is a highly sensitive technique in diagnosing musculoskeletal infectious lesions. It is especially useful in distinguishing abscesses from surrounding cellulitis/myositis. Lack of contrast enhancement rules out infection with a high degree of certainty. However, contrast enhancement cannot be used to reliably distinguish infectious from noninfectious inflammatory conditions.",
keywords = "Contrast enhancement, Infection, Magnetic resonance, Musculoskeletal",
author = "Katharine Hopkins and Li, {King C P} and Gabrielle Bergman",
year = "1995",
month = "7",
doi = "10.1007/BF00197059",
language = "English (US)",
volume = "24",
pages = "325--330",
journal = "Skeletal Radiology",
issn = "0364-2348",
publisher = "Springer Verlag",
number = "5",

}

TY - JOUR

T1 - Gadolinium-DTPA-enhanced magnetic resonance imaging of musculoskeletal infectious processes

AU - Hopkins, Katharine

AU - Li, King C P

AU - Bergman, Gabrielle

PY - 1995/7

Y1 - 1995/7

N2 - The purpose of this study was to assess whether gadolinium-enhanced magnetic resonance imaging (MRI) provides diagnostic information beyond that given by nonenhanced imaging in the evaluation of musculoskeletal infectious processes and whether it can be used for differentiating infectious from noninfectious inflammatory lesions. Magnetic resonance images performed with and without intravenous gadolinium-DTPA in 34 cases in which musculoskeletal infection had been clinically suspected were reviewed. Infectious lesionsincluding osteomyelitis, pyarthrosis, abscess, and cellulitis-were confirmed in a total of 22 cases: in 15 by biopsy or drainage and in 7 by clinical course. Our results show that gadolinium-DTPA-enhanced MRI is a highly sensitive technique in diagnosing musculoskeletal infectious lesions. It is especially useful in distinguishing abscesses from surrounding cellulitis/myositis. Lack of contrast enhancement rules out infection with a high degree of certainty. However, contrast enhancement cannot be used to reliably distinguish infectious from noninfectious inflammatory conditions.

AB - The purpose of this study was to assess whether gadolinium-enhanced magnetic resonance imaging (MRI) provides diagnostic information beyond that given by nonenhanced imaging in the evaluation of musculoskeletal infectious processes and whether it can be used for differentiating infectious from noninfectious inflammatory lesions. Magnetic resonance images performed with and without intravenous gadolinium-DTPA in 34 cases in which musculoskeletal infection had been clinically suspected were reviewed. Infectious lesionsincluding osteomyelitis, pyarthrosis, abscess, and cellulitis-were confirmed in a total of 22 cases: in 15 by biopsy or drainage and in 7 by clinical course. Our results show that gadolinium-DTPA-enhanced MRI is a highly sensitive technique in diagnosing musculoskeletal infectious lesions. It is especially useful in distinguishing abscesses from surrounding cellulitis/myositis. Lack of contrast enhancement rules out infection with a high degree of certainty. However, contrast enhancement cannot be used to reliably distinguish infectious from noninfectious inflammatory conditions.

KW - Contrast enhancement

KW - Infection

KW - Magnetic resonance

KW - Musculoskeletal

UR - http://www.scopus.com/inward/record.url?scp=0029061492&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029061492&partnerID=8YFLogxK

U2 - 10.1007/BF00197059

DO - 10.1007/BF00197059

M3 - Article

VL - 24

SP - 325

EP - 330

JO - Skeletal Radiology

JF - Skeletal Radiology

SN - 0364-2348

IS - 5

ER -