G-protein-coupled receptors: the new dopamine receptor subtypes

David K. Grandy, Olivier Civelli

    Research output: Contribution to journalArticlepeer-review

    29 Scopus citations

    Abstract

    The family of genes encoding G-protein-coupled dopamine receptors continues to grow with the recent cloning of a fifth member. The availability of these clones has revolutionized the dopamine receptor field. Expression of individual dopamine receptors is permitting the detailed analysis of their pharmacology and coupling to second messenger systems, while probes based on the receptors' nucleotide sequences are being used to gain new insights into their tissue distribution and genetics.

    Original languageEnglish (US)
    Pages (from-to)275-281
    Number of pages7
    JournalCurrent Opinion in Neurobiology
    Volume2
    Issue number3
    DOIs
    StatePublished - Jun 1992

    ASJC Scopus subject areas

    • Neuroscience(all)

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