@article{414b98b2f3414d20ba2762e6d9e27c8e,
title = "Fusiform correlates of facial memory in Autism",
abstract = "Prior studies have shown that performance on standardized measures of memory in children with autism spectrum disorder (ASD) is substantially reduced in comparison to matched typically developing controls (TDC). Given reported deficits in face processing in autism, the current study compared performance on an immediate and delayed facial memory task for individuals with ASD and TDC. In addition, we examined volumetric differences in classic facial memory regions of interest (ROI) between the two groups, including the fusiform, amygdala, and hippocampus. We then explored the relationship between ROI volume and facial memory performance. We found larger volumes in the autism group in the left amygdala and left hippocampus compared to TDC. In contrast, TDC had larger left fusiform gyrus volumes when compared with ASD. Interestingly, we also found significant negative correlations between delayed facial memory performance and volume of the left and right fusiform and the left hippocampus for the ASD group but not for TDC. The possibility of larger fusiform volume as a marker of abnormal connectivity and decreased facial memory is discussed.",
keywords = "Amygdala, Autism, Facial memory, Fusiform gyrus, Hippocampus",
author = "Trontel, {Haley G.} and Duffield, {Tyler C.} and Bigler, {Erin D.} and Alyson Froehlich and Prigge, {Molly B.D.} and Nielsen, {Jared A.} and Cooperrider, {Jason R.} and Cariello, {Annahir N.} and Travers, {Brittany G.} and Anderson, {Jeffrey S.} and Zielinski, {Brandon A.} and Andrew Alexander and Nicholas Lange and Lainhart, {Janet E.}",
note = "Funding Information: The project described was supported by Grant Numbers RO1 MH080826 (JEL, EDB, ALA, NL), RO1 MH084795 (JEL, PTF, NL), and KO8 MH092697 (JSA) from the National Institute Of Mental Health; Grant Numbers T32 HD07489 and the Hartwell Foundation (BGT), P30 HD003352-45 (Waisman Center Core Grant), and CHRCDA K12 HD001410 (BAZ) from the Eunice Kennedy Shriver NICHD, The Hartwell Foundation (BGT), and the Primary Children{\textquoteright}s Medical Center Foundation (BAZ). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Mental Health, the National Institute of Child Health & Development, or the National Institutes of Health. We thank former members of the Utah Autism CPEA for their assistance during the early stages of this project. We sincerely thank the children, adolescents, and adults with autism and the individuals with typical development, who participated in this study, and their families. The brain Imaging and Behavior Laboratory at BYU is partially supported by a donation from the Poelman Foundation. Although Dr. Bigler is the co-author of the TOMAL, he receives no royalties and reports no conflict of interest. The assistance of Tracy J. Abildskov and Jo Ann Petrie, is gratefully acknowledged. Funding Information: The project described was supported by Grant Numbers RO1 MH080826 (JEL, EDB, ALA, NL), RO1 MH084795 (JEL, PTF, NL), and KO8 MH092697 (JSA) from the National Institute Of Mental Health; Grant Numbers T32 HD07489 and the Hartwell Foundation (BGT), P30 HD003352-45 (Waisman Center Core Grant), and CHRCDA K12 HD001410 (BAZ) from the Eunice Kennedy Shriver NICHD, The Hartwell Foundation (BGT), and the Primary Children's Medical Center Foundation (BAZ). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Mental Health, the National Institute of Child Health & Development, or the National Institutes of Health. We thank former members of the Utah Autism CPEA for their assistance during the early stages of this project. We sincerely thank the children, adolescents, and adults with autism and the individuals with typical development, who participated in this study, and their families. The brain Imaging and Behavior Laboratory at BYU is partially supported by a donation from the Poelman Foundation. Although Dr. Bigler is the co-author of the TOMAL, he receives no royalties and reports no conflict of interest. The assistance of Tracy J. Abildskov and Jo Ann Petrie, is gratefully acknowledged. Publisher Copyright: {\textcopyright} 2013 by the authors.",
year = "2013",
month = sep,
doi = "10.3390/bs3030348",
language = "English (US)",
volume = "3",
pages = "348--371",
journal = "Behavioral Sciences",
issn = "2076-328X",
publisher = "Multidisciplinary Digital Publishing Institute",
number = "3",
}