Fulminant thrombotic thrombocytopenic purpura in a patient with the limited form of scleroderma: Successful outcome using plasma exchange

S. Cookson, M. L. Krueger, R. M. Bennett

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

A 35-year-old woman with a 20-year history of limited scleroderma presented with a 7-day history of low grade fever associated with a red colored urine, 2 days of jaundice and lower extremity petechiae. On admission she had a rapidly deteriorating neurological status associated with thrombocytopenia and microangiopathic anemia. A diagnosis of thrombotic thrombocytopenic purpura (TTP) was made and treatment begun with fresh frozen plasma, plasma exchange and pulse corticosteroids. After a stormy 28-day hospital course she was discharged without residual problems of TTP.

Original languageEnglish (US)
Pages (from-to)900-901
Number of pages2
JournalJournal of Rheumatology
Volume18
Issue number6
StatePublished - 1991
Externally publishedYes

Keywords

  • limited scleroderma
  • plasma exchange
  • plasmapheresis
  • thrombotic thrombocytopenic purpura

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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