Fulminant thrombotic thrombocytopenic purpura in a patient with the limited form of scleroderma: Successful outcome using plasma exchange

S. Cookson, M. L. Krueger, R. M. Bennett

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    18 Scopus citations

    Abstract

    A 35-year-old woman with a 20-year history of limited scleroderma presented with a 7-day history of low grade fever associated with a red colored urine, 2 days of jaundice and lower extremity petechiae. On admission she had a rapidly deteriorating neurological status associated with thrombocytopenia and microangiopathic anemia. A diagnosis of thrombotic thrombocytopenic purpura (TTP) was made and treatment begun with fresh frozen plasma, plasma exchange and pulse corticosteroids. After a stormy 28-day hospital course she was discharged without residual problems of TTP.

    Original languageEnglish (US)
    Pages (from-to)900-901
    Number of pages2
    JournalJournal of Rheumatology
    Volume18
    Issue number6
    StatePublished - Jan 1 1991

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    Keywords

    • limited scleroderma
    • plasma exchange
    • plasmapheresis
    • thrombotic thrombocytopenic purpura

    ASJC Scopus subject areas

    • Rheumatology
    • Immunology and Allergy
    • Immunology

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