Frequency-dependent enhancement of basilar membrane velocity during olivocochlear bundle stimulation

David F. Dolan, Meng He Guo, Alfred L. Nuttall

Research output: Contribution to journalArticlepeer-review

45 Scopus citations

Abstract

Basilar membrane (BM) velocity responses were measured in the presence of olivocochlear bundle (OCB) stimulation. Frequency threshold tuning curves (FTCs) were derived from tone-evoked input-output (I/O) functions. Efferent nerve activation produced decreases in velocity amplitude for frequencies around best frequency (BF) at low stimulus levels with little or no effect for stimuli well below the BF. A level-dependent efferent reduction/enhancement of BM velocity was found for certain stimulus frequencies above the BF. Efferent activation either had no effect or caused small reductions in the velocity response produced by low level sound, whereas, at higher stimulus levels, efferent activation increased the velocity response. The derived FTCs, therefore, showed criterion-dependent changes with efferent activation. For low BM criterion velocities, FTCs showed the classic desensitization of the tip region without a shift of BF. Some BM velocity criterion values showed FTCs with an expanded high-frequency response area, also without a shift of BF. The results suggest that the effect of OCB activation changes the gain of the voltage-dependent outer hair cell motility such that BM velocity response neat BF is decreased while increasing the response for tones well above BF.

Original languageEnglish (US)
Pages (from-to)3587-3596
Number of pages10
JournalJournal of the Acoustical Society of America
Volume102
Issue number6
DOIs
StatePublished - Dec 1 1997

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Acoustics and Ultrasonics

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