Frequency and etiology of unexplained bilateral hydronephrosis in patients with breast cancer: Results of a longitudinal CT study

Ari J. Kane, Zhen J. Wang, Aliya Qayyum, Benjamin M. Yeh, Emily M. Webb, Fergus Coakley

Research output: Contribution to journalArticle

6 Scopus citations


We retrospectively reviewed the records of 153 patients with breast cancer undergoing serial abdominal computed tomography (CT). During a median follow-up of 40 months, 2 (1.4%) of 153 patients developed bilateral hydronephrosis in the absence of radiologically visible obstructing pathology. Surgery confirmed malignant infiltration of the ureters by metastatic lobular carcinoma in both patients, suggesting that new unexplained bilateral hydronephrosis on serial CT in patients with breast cancer is likely to reflect infiltrative retroperitoneal involvement of the ureters by metastatic lobular carcinoma.

Original languageEnglish (US)
Pages (from-to)263-266
Number of pages4
JournalClinical Imaging
Issue number4
Publication statusPublished - Jul 2012
Externally publishedYes



  • Breast carcinoma
  • CT
  • Hydronephrosis
  • Metastasis
  • Ureter

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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